补佳乐用于防止再次宫腔粘连的疗效观察  

Observation on clinical efficacy of progynova in prevention of secondary intrauterine adhesion

作　　者：张莘[1] 张丙忠[1] 冯淑英[1] 陈勍[1] 彭永排[1] 

机构地区：[1]中山大学附属第二医院妇产科,广东广州510120

出　　处：《中国妇幼保健》2010年第4期559-560,共2页Maternal and Child Health Care of China

摘　　要：目的:评价补佳乐用于防止术后再次宫腔粘连的效果。方法:2005年1月～2007年12月因宫腔粘连行宫腔镜检查并行宫腔粘连切开术患者52例,术后放置宫内节育环后分为A组和B组。B组患者术后加用补佳乐2 mg/日,联合安宫黄体酮序贯治疗,共计29例;A组患者选用复方孕二烯酮片1片/日,共23例,共用药3个周期,定期复查肝肾功能等项目,再行宫腔镜检查并取出宫内节育环。结果:所有患者均未见肝肾功能损害,再次宫腔镜检查,补佳乐组1例患者再次发生宫腔粘连,其他患者预后恢复良好;A组9例患者再次出现宫腔粘连,差异有统计学意义。结论:宫腔粘连切开分离术后,补佳乐是防止术后再次宫腔粘连的有效药物。Objective： To evaluate the clinical efficacy of progynova in prevention of secondary, intrauterine adhesion. Methods： 52 cases underwent intrauterine adhesion section after hysteroscopy from January 2005 to December 2007, followed by an insertion of an intrauterine contraceptive device, then they were divided into group A and group B. 29 cases in group B took prngynova, 2 mg per day, combined with sequential therapy of medroxyprogesterone acetate; 23 cases in group A took compound gestodene tablets, 1 tablet per day for three cycles, liver function and renal function were reexamined regularly, then hysteroscopy was conducted to remove the intrauterine contraceptive device. Results ： The liver function and renal function of all cases were normal, all the cases recovered well except one case in progynova group; recurrence was found in 9 cases in group A, there was significant difference. Conclusion： After intrauterine adhesion section, progyuova is an effective medicine in prevention of secondary intrauterine adhesion.

关 键 词：宫腔粘连 补佳乐 复方孕二烯酮片 

分 类 号：R713.4[医药卫生—妇产科学]