高原红细胞增多症患者血清EPO含量变化及其意义  

LEVELS AND SIGNIFICANCE OF SERUM ERYTHROPOIETIN (EPO) IN PATIENTS WITH HIGH ALTITUDE POLYCYTHEMIA

作　　者：李素芝[1] 牟信兵[1] 薛增军[1] 郑碧海[1] 

机构地区：[1]西藏军区总医院高山病防治研究中心

出　　处：《高原医学杂志》1998年第3期30-31,共2页Journal of High Altitude Medicine

摘　　要：目的：探讨ＥＰＯ在高原红细胞增多症发病机制中的作用。方法：采用放射免疫法检测了高红症患者、高原移居健康者及平原健康人外周血清中的ＥＰＯ含量。结果：高红症患者及高原健康人血清ＥＰＯ水平显著高于平原对照组（Ｐ＜０．０１）；而高红症患者血清ＥＰＯ水平同高原健康人相比无显著性差异。Objective:To investigate the role of EPO in the pathogenesis of high altitude polycythemia(HAPC).Methods:Serum level of EPO in 15 patients with HAPC,15 high altitude healthy subjects (as controls) and 15 lowland healthy subjects (as controls) was measured by using radioimmunoassay.Results:The levels of EPO were increased significantly ( P <0 01) in HAPC patients and high altitude controls than in lowland controls.The levels of EPO in HAPC patients were same as the high altitude controls( P >0 05).Conclusion:EPO may play an important role in the pathogenesis of HAPC.

关 键 词：高原 红细胞增多症 EPO 缺氧 

分 类 号：R555.102[医药卫生—血液循环系统疾病]