噻虫胺的合成  

Synthesis for Clothianidin

作　　者：张明媚[1] 孙克[1] 吴鸿飞[1] 杨浩[1] 张弘[1] 赵静[1] 杨贺选[1] 

机构地区：[1]沈阳化工研究院有限公司,沈阳110021

出　　处：《农药》2010年第2期94-96,共3页Agrochemicals

摘　　要：噻虫胺是一种高效、广谱、低毒的新烟碱类杀虫剂。综述了噻虫胺的合成方法,并对其中一种合成路线进行了详细的研究,即以硝基胍、2,3-二氯丙烯为起始原料,经过分解中间体1-(2-氯噻唑-5-甲基)-2-硝基亚胺基-3,5-二甲基-六氢-1,3,5-三嗪制备噻虫胺,总收率可达58.6%。此工艺路线具有选择性高、反应条件温和、反应时间短、产品纯度高、易于实现工业化生产等特点。Clothianidin is one of new neonicotinoids with good efficacy, broad spectrum and low toxicity for the nontargeted species. The synthesis of clothianidin was introduced in this paper. And one of the methods was researched in detailed in this paper. It started from nitroguanidine and 2,3-dichloropropene, and resolve the material named N-（1- （（2-chlorothiazol-5-propyl-1,3,5-triazinan-2-ylidene） nitamide into clothianidin. The method was suitable for industrial preparation by its many advantages such as effective activator, mild reaction conditions, simple experimental procedure, high selectivity and purity.

关 键 词：新烟碱 杀虫剂 噻虫胺 合成 

分 类 号：TQ453.2[化学工程—农药化工]