甲磺酸罗哌卡因混合利多卡因骶管麻醉用于小儿尿道下裂的效果观察  

Effects of Ropivacaine Mesylate Injection plus Lidocaine with Sacral Anaethesia for Pedo-hypospadia Operations

作　　者：程洁[1] 黄德樱[1] 

机构地区：[1]武汉市妇女儿童医疗保健中心麻醉科,湖北武汉430016

出　　处：《医学信息》2010年第2期380-382,共3页Journal of Medical Information

摘　　要：目的 探讨甲磺酸罗哌卡因混合利多卡因小儿骶管阻滞麻醉在小儿尿道下裂手术中应用的效果观察。方法 选择择期尿道下裂惠儿75例，随机分成三组，每组25例。A组：注入1％利多卡因，B组：注入0．29％甲磺酸罗哌卡因加1％利多卡因混合液，C组：注入0．35％甲磺酸罗哌卡因。均用0．9％生理盐水适当稀释，容量为0．8ml／kg骶管穿刺前均给予氯氨酮2mg／kg静脉注射。结果 三组患儿HR、RR、NIBP、SpO2差异无显著性，三组麻醉效果均满意。感觉神经阻滞起效时间A组短于B、C组（P〈0·01），B组短于c组（P〈0·01）；总感觉阻滞时间与运动神经阻滞时间A、B、C三组依次递增fP均〈O·01）。结论 甲磺酸罗哌卡因混合利多卡因用于小儿骶管麻醉，起效快，效果好，持续时间长，镇痛效果好，适于小儿尿道下裂手术麻醉。Objective To observe the caudal block effects of Ropivacaine Mesylate Injection plus Lidocaine in pedo-hypospadia operations. Methods 75 pediatric patients with hypospadia were randomly divided into three groups with evenly 25 cases each： group A, B, and C, respectively treated with 1% Lidocaine, 0.29% Ropavacaine plus 1% Lidocaine, and 0.35% Ropavacaine. All solutions were diluted into proper concentration with 0.9% Natrium Solution, and then injected into sacral hiatus with the volume of 0.8ml/kg after intravenous injection of ketamine 2mg/kg. Results All children in the three groups showed no differences in comparation of HR ,RR,NIBP,SpO2, and boasted satisfying anesthesia effects as well. Average onset time of blockage effects on sensory nerves in group A was significantly shorter than group B and C, with the former shorter than the latter. Total time of blockage on sensory nerves in group A, B, C, and that on motor nerves was found increased by degrees consecutively. Conclusions Ropivacaine Mesylate Injection plus Lidocaine is suitable for use in caudal block on pediatric patients for its advantages, such as satisfying analgesia, instant effects, and long duration.

关 键 词：甲磺酸罗哌卡因混合利多卡因 骶管麻醉 尿道下裂 小儿 

分 类 号：R927.2[医药卫生—药学] R473.72