Ames试验对海产贝类遗传毒性的检测  

Genotoxicity assays of shellfish by Ames test

作　　者：刘材材[1,2] 项凌云[1] 王金辉[1,2] 张昊飞[1] 叶属峰[1] 徐韧[1] 程祥圣[1] 

机构地区：[1]上海交通大学环境科学与工程学院,上海200240 [2]国家海洋局东海环境监测中心,上海200137

出　　处：《海洋环境科学》2010年第1期124-126,138,共4页Marine Environmental Science

基　　金：上海市科委登山行动计划(06dz12015);上海市科委长三角联合攻关项目(062358101);国家海洋局近岸海域生态环境重点实验室资助项目(200812)

摘　　要：采用Ames试验结合小白鼠生物学试验对贝类腹泻性贝毒(diarrhetic shellfish poisoning,DSP)的提取物进行了遗传毒性初步研究。结果表明:4份贝类样品不同程度地受到了遗传毒物的污染,7份贝类样品受到腹泻性贝毒污染。同时本文也从实践上证明在我国海洋环境监测开展Ames试验对贝类遗传毒性检测具有极为重要的意义。Abstract：This paper deals with the preliminary genotoxicity of the extraction of diarrhetic poison from the shellfish by the Ames test and mouse bioassay. The results showed that four samples were polluted by the mutagenicity with different degrees and seven samples were polluted by the diarrhetic shellfish poison. The genotoxieity assays of shellfish by the Ames test should be treated as a routine marine environment monitoring procedure in China.

关 键 词：贝类 AMES试验 遗传毒性 腹泻性贝毒 小白鼠生物学试验 

分 类 号：Q331[生物学—遗传学]