1,3-二(4-苯胺)金刚烷的合成  

Synthesis of 1,3-bis(4-aminophenyl) adamantane

作　　者：孔黎春[1] 胡晓春[1] 

机构地区：[1]浙江师范大学化学与生命科学学院,浙江金华321004

出　　处：《浙江师范大学学报（自然科学版）》2010年第1期79-81,共3页Journal of Zhejiang Normal University:Natural Sciences

基　　金：浙江省教育厅科研项目(Y200805661)

摘　　要：以1-金刚烷醇与乙酰苯胺为原料,在浓硫酸介质中室温下发生傅克烷基化反应,合成得到1,3-二(4-乙酰氨基苯基)金刚烷,然后将其水解合成了1,3-二(4-苯胺)金刚烷,合计收率为64%,产物结构经红外光谱、1H和13C核磁共振谱表征.该方法产率较高,大大方便了1,3-金刚烷二芳基衍生物的合成.Firstly, 1,3-bis（4-acetylaminopheny） adamantine was synthesized as a result of Friedel-Crafts alkylation of 1-adamantanol and Acetanilide with 98% sulfuric acid as the medium at room temperature. Secondly, 1,3-his （4-aminophenyl） adamantane was formed by hydrolysis of 1,3-his （ 4-acetylaminopheny ） adamantine. The total yields rate was 63% and its structure was confirmed by IR, ^1H NMR and ^13C NMR. This route had the advantage of higher yields, which would make the synthesis of 1,3-diaryladamantane more convenient.

关 键 词：1-金刚烷醇 1 3-二(4-乙酰氨基苯基)金刚烷 1 3-二(4-苯胺)金刚烷 合成 

分 类 号：O621.25[理学—有机化学]