Amplatzer封堵器治疗房间隔缺损疗效及安全性评价  

Evaluation of the Effect and Safety of Amplatzer Defect

作　　者：崔波[1] 郭莹[1] 张翼[1] 

机构地区：[1]湖南省人民医院心内科,湖南长沙410005

出　　处：《医学临床研究》2010年第1期64-66,共3页Journal of Clinical Research

摘　　要：【目的】探讨用Amplatzer封堵器闭合房间隔缺损的临床疗效、安全性及其并发症，并与心脏直视手术进行对比。【方法】对2002年1月至2007年12月在本院实行Amplatzer封堵器介入治疗的68例患者（试验组）以及心脏直视手术的60例患者（对照组）的疗效、安全性及并发症进行分析比较。【结果】试验组和对照组的成功率分别为97．1％和100％，而在住院时间、并发症发生率、死亡率等方面实验组均优于对照组（P〈0．05）。【结论】运用Amplatzer封堵器闭合房间隔缺损成功率高，残余分流发生率低，并发症发生率低，是一种安全有效的治疗方法。对适合经导管封堵的ASD，可作为首选治疗方法。[Objective]To evaluate the clinical results, securities and complications of transcatheter closure of atrial spetal defect（ASD） with Amplatzer occluder. [Methods] A total of 226 patients with ASD were enrolled from Jan. 2002 to Dec. 2007. Among them, 128 patients underwent transcatheter occlusion with Amplatzer oecluder, while 98 eases were treated surgically. The effectiveness, securities and complications were compared between the two groups. [Methods] The success rate of Amplatzer group was 96.9%, while the success rate of surgery group was 100%. The hospital stay of Amplatzer group was shorter than that of the surgery group. The corriplication incidence and death rate of Amplatzer group were lower than those of the surgery group （ P 〈0.05）. [Conclusion] Transcatheter closure of ASD with Amplatzer oeeluders is a safe and efficient nonsurgieal method for its high success rate, low residual shunt rate and low complication rate.

关 键 词：房间隔缺损/外科学 

分 类 号：R654.1[医药卫生—外科学]