吸烟对血液过氧化与抗氧化平衡的影响  

Effects of cigarette smoking on oxidative and antioxidative balance of human blood

作　　者：张建华[1] 张光辉 薛秀兰[1] 崔华娟 

机构地区：[1]佳木斯大学医学院病生教研室

出　　处：《黑龙江医药科学》1998年第5期27-28,共2页Heilongjiang Medicine and Pharmacy

摘　　要：比较吸烟与不吸烟人静脉血血浆及红细胞脂质过氧化物-丙二醛（MDA）含量，血浆及红细胞超氧化物歧化酶（SOD）活力、全血谷胱甘肽过氧化物酶（GSH－Px）活力及血浆总抗氧化能力（AOA）．结果表明：吸烟组血浆及红细胞MDA的含量高于不吸烟组（P＜0．01），红细胞SOD含量高于不吸烟组（P＜0．01），血浆SOD、全血GSH－Px活力．血浆AOA均低0于不吸烟组（P＜0．01，P＜0．05，P＜0.05）．提示长期吸烟可使血中氧化与抗氧化失去平衡。The MDA levels in erythrocyte and plasma, the SOD activity in erythrocyte and plasma, the blood GSH-Px activity and the AOA were compared in smokers and non-smokers. It was found that erythrocyte MDA level, plasma MDA and ewtrocyte SOD of smokers were significantly higher than those of the non-smokers (P<0.01). Plasma SOD, blood GSH-Px and plasma AOA of smokers were lower than those of the non-smokers (P<0.01, P<0.05, P<0.05). These results suggest that cigarette smoking might cause an imbalancc between oxidation and antioxidation in blood.

关 键 词：红细胞 丙二醛 超氧化物歧化酶 吸烟 

分 类 号：R163[医药卫生—公共卫生与预防医学]