利用酶催化法拆分烯丙菊醇的研究  

A Study on Resolution of Allethrolone via Enzyme Catalysis

作　　者：肖海波[1] 吴慧君[2] 

机构地区：[1]上海第二医科大学化学教研室,上海200025 [2]华东师范大学化学系,上海200062

出　　处：《农药》1998年第11期19-21,31,共4页Agrochemicals

摘　　要：在有机溶剂中用酶催化的不对称酯交换反应拆分烯丙菊醇，并探索了分离产物的新途径。醇的光学纯度可达90％以上。本方法具有操作简单、酶可重复使用等特点，并具有工业生产前景。此外，又进行了把无效体（R）－烯丙菊醇转化成有效体的工作。This paper described the resolution of allethrolone via enzyme - catalyzed steroospecific transesterification in organic media and a new way of separating (S) - allethrolone from stereospecific transesterification product. Optical purities are greater than 90%, enzyme can be recycled. This method is simple and applicable to industry. In addition, a new process for utilizing the unwanted waste (R) - allethrolone was studied.

关 键 词：酶催化法 拆分 烯丙菊醇 杀虫剂 中间体 

分 类 号：TQ453.04[化学工程—农药化工]