氨基苯磺酰胺-CdTe量子点耦合物的制备及表征  

Preparation and Characterization of the Complex of CdTe Quantum Dots Coupled with Sulfanilamide

作　　者：朱奎[1] 吕磊[2] 李金贵[2] 丁双阳[1] 

机构地区：[1]中国农业大学动物医学院,北京100193 [2]扬州大学兽医学院,扬州225009

出　　处：《理化检验（化学分册）》2010年第1期8-12,共5页Physical Testing and Chemical Analysis(Part B:Chemical Analysis)

基　　金：国家自然科学基金(30671585);"十一五"国家科技支撑计划(2006BAK10B09)

摘　　要：以巯基丙酸作为稳定剂合成水溶性碲化镉(CdTe)量子点,采用3种偶联方法将氨基苯磺酰胺(SN)与水溶性CdTe量子点进行偶联以制备氨基苯磺酰胺-CdTe量子点耦合物。通过紫外-可见光谱、荧光光谱、透射电子显微镜和傅里叶红外变换光谱分别表征了耦合物的结构和部分光谱学特性。结果表明:巯基丙酸的巯基中硫原子和羧基中氧原子与CdTe量子点纳米微粒表面的富镉离子发生了配位作用,也证实水溶性CdTe量子点与氨基苯磺酰胺的耦合主要是通过量子点周围巯基丙酸羧基(-COOH)中的氧原子与SN的胺基(-NH2)形成分子间氢键实现的。氨基苯磺酰胺-CdTe量子点耦合物对大肠杆菌增殖的生物学试验表明,耦合物对大肠杆菌有一定的抑制作用,进一步说明氨基苯磺酰胺-CdTe量子点耦合物制备成功。Three different methods were described for preparation of the coupled complex formed between sulfanilamide （SN） and water soluble CdTe quantum dots （QDts）, which were prepared by wrapping nanoparticles of the CdTe QD＇s with mercaptopropionic acid （MPA）. Structure and part of its spectroscopic features were characterized by UV-VIS spectrometry, fluorescence spectrometry, transmission electron microscopy and FT-IR spectrometry. As shown by the results, coordination was carried out through the reaction between the S of --SH group and the O of --COOH group in MPA and Cd2＋ ions which were rich on the surface of the CdTe QD nanoparticles, and coupling reaction between the water soluble CdTe QD＇s and SN was achieved through the intramolecular hydrogen bond formed between the O of --COOH group of MPA, surrounding the QD＇s, and the --NH2 group of SN. And further, inhibitory effect of the coupled complex of CdTe QD＇ s-SN on proliferation of colon bacillus was also observed by biological test. As a conclusion, preparation of the coupled complex of CdTe QD＇s with SN was proved to be surccessful by all the experimental results.

关 键 词：院  扬州 225009 CDTE量子点 SN-CdTe耦合物 制备 表征 

分 类 号：O657.39[理学—分析化学]