用于评估心室辅助装置的人体循环系统半实物仿真模型  

A Hardware-in-the-loop Simulation Model of the Cardiovascular System for Ventricular Assist Device Evaluation

作　　者：李虹磊[1] 杨明[1] 李世阳[1] 

机构地区：[1]上海交通大学仪器科学与工程系,上海200240

出　　处：《中国医疗器械杂志》2010年第1期16-20,共5页Chinese Journal of Medical Instrumentation

基　　金：国家自然科学基金资助项目(30670524;30540025);上海市浦江人才计划(07pj14054)

摘　　要：将心室辅助装置的动态物理性能测试与成熟的人体心血管系统数学模型相结合,提出了一种便捷准确的心室辅助装置评估方法。该方法对自制气动直接心室辅助装置样机进行了测试,研究了该辅助装置与心血管系统的相互作用,并进行了血液动力学进行仿真分析。结果表明,该方法对于研究心血管系统受心室辅助的影响和优化心室辅助装置的结构设计以及控制算法都有很积极的意义。This paper presents a novel technique for evaluating the performance of ventricular assist devices in vitro, innovatively combining dynamic physical testing of assist devices with a mature, numerical human cardiovascular model. Based on this technique, one self-made direct mechanical ventricular assistance （DMVA） prototype is tested. With the true representation of device performance in vivo, the real-time interactions between DMVA and the cardiovascular system are captured and studied. Hemodynamic simulations under DMVA are performed. Experimental results demonstrate that it provides a useful tool for the study of device assist impact on the cardiovascular system as well as the improvement of device structure and effectiveness of control mechanism.

关 键 词：半实物仿真 心室辅助装置 心血管系统 建模 

分 类 号：R318.1[医药卫生—生物医学工程]