乙酰水杨酸制备双核水杨酸锰(Ⅳ)配合物  

Process for Preparing Binuclear Manganese(Ⅳ) Complex via Acetylsalicylic Acid

作　　者：邱祖民[1] 吕亚洲[1] 刘达波[1] 林磉[2] 

机构地区：[1]南昌大学环境与化学工程学院,江西南昌330031 [2]同济大学职业技术教育学院,上海200070

出　　处：《南昌大学学报（工科版）》2009年第4期307-312,共6页Journal of Nanchang University(Engineering & Technology)

基　　金：江西省自然科学基金资助项目(0620060);江西省教育厅科技资助项目(赣教技字[2006]11号)

摘　　要：用乙酰水杨酸作配体,通过与人体所必需的微量元素——锰配位合成出双核水杨酸锰(Ⅳ)配合物:以乙酰水杨酸和碳酸氢钠反应,再在70℃水浴中与硫酸锰反应,加沉淀剂叔丁醇,放置结晶,将得到的产物用扩散法结晶得到双核水杨酸锰(Ⅳ)配合物晶体,分析了使用乙醇和苯组合的混合溶剂做结晶更佳,指出了未得到乙酰水杨酸锰的原因。通过单晶衍射、FT-IR、质谱进行了表征,并对配合物的热重、紫外可见光谱、荧光光谱以及磁学性能进行了考察,该配合物在生物医药、荧光性能以及磁性性能方面具有广泛的应用价值。The binuclear manganese（Ⅳ） [Mn2（Hsal）4（OH）4]（Hsal=o-OHC6H4COO） complex was synthesized by acetylsalicylic acid ligand with manganese which is trace elements necessary for the human.The synthesis of complex was carried out by reaction of NaHCO3 with acetylsalicylic acid（equimolar amounts） in water,and mixed with MnSO4（the mole rate of MnSO4：acetylsalicylic acid=1：2） under stirring at 70 ℃ for 30 min,with tert-butyl alcohol as precipitant,collected insoluble material from the solution by filtration,then crystallization growth obtained by solvent diffusion method in ethanol benzene.The mixed solvents was analyzed to be better.Unfortunately we did not get manganese acetylsalicylate,the reason was directed.Single crystal diffraction,FT-IR,mass spectrum of complex was used.TG,UV-Vis,fluorescence spectrum and magnetic properties were inspected.Biological pharmaceutical functions,fluorescence and magnetic property of complex can be widely developed and utilized.

关 键 词：乙酰水杨酸 水杨酸锰 阿司匹林锰 荧光 

分 类 号：O164.7[理学—数学]