人博卡病毒与AECOPD相关性研究  

Correlation study of human bocavirusn and acute exacerbation of chronic obstructive pulmonary disease

作　　者：刘永平[1] 刘春云 肖承康 

机构地区：[1]湖南中医药大学生理学教研室,湖南长沙410007 [2]江西赣南肺科医院呼吸科,江西赣州341000

出　　处：《临床肺科杂志》2010年第3期313-314,共2页Journal of Clinical Pulmonary Medicine

摘　　要：目的探讨人博卡病毒(HBoV)与慢性阻塞性肺疾病急性加重(AECOPD)的关系。方法PCR检测2008年11月～2009年4月55例慢性阻塞性肺疾病(COPD)患者诱导痰标本的HBoV,其AECOPD患者26例(47.3%),稳定期COPD患者29例(52.7%)。结果共发现2例HBoV阳性,AECOPD患者和稳定期COPD患者各1例,阳性率分别为3.85%和3.45%。结论HBoV不是AECOPD呼吸道感染的的重要病原,双者之间无关联性。Objective To determine the frequency and clinical relevance of HBoV infection in adult patients with acute exacerbation of chronic obstructive pulmonary disease （AECOPD）. Methods We retrospectively tested 55 COPD patients, 26 （47. 3% ） with AECOPD and 29 （52. 7% ） with stable disease, of whom induced sputum had been obtained for the presence of HBoV deoxyribonucleic acid （DNA）. Results HBoV DNA was detected in two patients （3.64%）. Of those, one patient had AECOPD. Thus, the frequency of HBoV infection demonstrated to be low in both AECOPD （3.85%） and stable COPD （3.45%）. Conclusion HBoV detection is infrequent. A major role of HBoV infection in adults with AECOPD is unlikely.

关 键 词：人博卡病毒 慢性阻塞性肺疾病 急性加重 急性呼吸道感染 

分 类 号：R563.9[医药卫生—呼吸系统]