药源性低血糖症28例临床分析  

Clinical features and emergency management of drug-induced hypoglycemia

作　　者：段丽君[1] 江霞[1] 

机构地区：[1]天津市第一中心医院内分泌科,天津300192

出　　处：《山西医科大学学报》2010年第2期147-149,共3页Journal of Shanxi Medical University

摘　　要：目的探讨药源性低血糖症的发病及临床特征,以提高早期诊断及救治水平。方法回顾性进行临床总结,分析28例药源性低血糖症的临床资料和治疗经过。结果全部病例均为急性起病,血糖范围在0.48-3.20mmol/L;其中以脑功能障碍为首发症状及伴随该临床表现者16例(占57.1%)。发病因素与降糖药物用法不当、药物超量、用药与进餐量不匹配、首选强效降糖药、中西药配伍不适、用药后过迟进食等有关。28例经临床及时确诊,应用高渗糖等治愈率达100%。结论早期诊断低血糖症是治疗成功的关健所在;加强合理用药是有效预防药源性低血糖症的根本措施。Objective To investigate the clinical characteristics of drug-induced hypoglycemia,and to improve its early diagnosis and treatment. Methods Data of 28 cases of drug-induced hypoglycemia were retrospectively analyzed. Results All the cases were acute, and the blood glucose ranged from 0.48 mmol/L to 3.20 mmol/L. The first clinical feature manifested the brain dysfunction in 16 cases （57.1% ）. The incidence was related with the improper use of hypoglycemic drugs, the overdose, the unsuitable amount of medication and meals, the use of potent hypoglycemic drugs, the inappropriate mix of Chinese and western medicine, and eating late after treatment. After being diagnosed timely and taking hypertonic glucose,all patients recovered and the curative rate was 100%. Conclusion Early diagnosis and evaluation is the key for the successful treatment. To strengthen the rational use of medicines is a fundamental measure for the effective prevention of drug-induced hypoglycemia.

关 键 词：低血糖症 脑功能障碍 糖尿病 

分 类 号：R587.3[医药卫生—内分泌]