2009甲型H1N1流感病毒新进展  

An update of 2009 influenza A (H1N1) virus

作　　者：李广波[1] 潘欣[1] 

机构地区：[1]第二军医大学微生物学教研室,上海医学硕士研究生200433

出　　处：《医学研究生学报》2010年第1期90-93,共4页Journal of Medical Postgraduates

基　　金：国家自然科学基金(30170891);教育部留学回国人员科研启动基金(教外司留2008-890-2);全军"十五"科研规划面上项目(01MA144)

摘　　要：甲型猪源性流感病毒属正粘病毒科,其可引起猪、禽和人的上呼吸道感染。2009年3月在美国和墨西哥的流感样患者的呼吸道标本中检测出新的不能分型的甲型流感病毒,并经确认为甲型H1N1流感病毒(简称2009甲型H1N1流感病毒)。这种病毒在美国和墨西哥引起暴发流行,并蔓延到世界各地,引起一些感染者死亡。文中综述了2009甲型H1N1流感病毒在基因分型、抗原特征、传播特点、致病特点、治疗等方面与已知各流感病毒不同的特征。Swine influenza A virus belongs to the family of Orthomyxoviridae, which can cause upper respiratory tract infection in swine, avian and human. The influenza A virus that could not be sub-typed was detected from the respiratory tract specimens of patients with influenza-like symptoms in March 2009 in USA and Mexico, followed by identification of a novel swine-origin influenza A （H1N1） virus （S-OIV）, which led to an epidemic outbreak in the above two countries and then spread all over the world, causing quite a few deaths. S-OIV differs from other influenza viruses in genotyping, antigenic characteristics, propagating characteristics, pathogenic characteristics and therapies.

关 键 词：甲型H1N1流感病毒 流感病毒基因型 抗原变异 RT—PCR 

分 类 号：R373.1[医药卫生—病原生物学]