2型糖尿病高尿酸血症患者检测一氧化氮的意义  

Study on significance of nitric oxide detection in hyperuricemia of type 2 diabetes mellitus

作　　者：廖洪利[1] 米叶赛尔.阿布都 田刚[2] 

机构地区：[1]新疆喀什地区第一人民医院检验科,新疆喀什844000 [2]天津公安医院检验科,300040

出　　处：《检验医学与临床》2010年第3期225-226,共2页Laboratory Medicine and Clinic

摘　　要：目的探讨一氧化氮(NO)与2型糖尿病高尿酸血症的关系。方法提取76例2型糖尿病(T2DM)无高尿酸血症患者(B组)、124例T2DM合并高尿酸血症患者(C组)及100例健康人(A组)的血清,测定其NO代谢产物硝酸盐和亚硝酸盐(NOx)水平。结果T2DM无高尿酸血症组比T2DM合并高尿酸血症组NOx水平高(P<0.05)。结论检测患者血清一氧化氮水平是诊断2型糖尿病高尿酸血症的敏感指标。Objective To investigate the association of nitric oxide （NO） with hyperuricemia in type 2 diabetics. Methods In 76 patients without hyperuricemia in type 2 diabetics（group B） ,124 patients with hyperuricemia in type 2 diabetics（group C） and 100 healthy controls （group A）, NOx was determined by reagent analysis. Results Compared with group C, there was higher NOx level in group B. There was significant difference between two groups （P〈0.05）. Conclusion NO is a vital index for diagnosis of hyperuricemia in type 2 diabetics.

关 键 词：2型糖尿病 高尿酸血症 一氧化氮 

分 类 号：R587.1[医药卫生—内分泌]