新疆某地维吾尔族男性吸毒者KSHV血清流行病学初步分析  

Seroepidemiology of Kaposi's Sarcoma-associated Herpesvirus in Uigur Male Drug Users from A Place in Xinjiang

作　　者：杨培荣[1] 郭淑霞[2] 谭晓华[2] 杨磊[2,3] 付碧石[4] 王林定[4] 张景玉[2] 张国宁[2] 

机构地区：[1]宝鸡市疾病预防控制中心,宝鸡721000 [2]石河子大学医学院,石河子832002 [3]杭州师范大学医药卫生管理学院,杭州310036 [4]中国科学院武汉病毒研究所,武汉430071

出　　处：《石河子大学学报（自然科学版）》2010年第1期68-71,共4页Journal of Shihezi University(Natural Science)

基　　金：科技部国际合作项目(2005DFA30780);国家自然科学基金项目(30700687);新疆兵团科技攻关医药卫生专项(05GG36)

摘　　要：为进一步研究HIV-KSHV感染相关疾病提供基础资料,利用ELISA法检测KSHV潜伏期LANA1、溶解期ORF65、K8.1抗原抗体,采用χ2检验分析有关数据,分析了新疆某地维吾尔族男性吸毒人群的KSHV血清流行病学的特点。吸毒人群主要以注射吸毒者为主(184/199,92.5%),在199份吸毒者血清中共检测到KSHV阳性血清60份,KSHV血清阳性率是30.6%;χ2检验分析显示,年龄、职业、文化程度、婚姻状况、HIV-1血清状态、吸毒方式以及吸毒年限均与KSHV血清阳性率无关,该吸毒人群中KSHV感染率较高,表明KSHV普遍存在于新疆某地维族男性吸毒人群。The aim of this study is to explore the primary features of Seroepidemiology of Kaposi＇s Sarcomaassociated Herpesvirus in Uigur male drug users from a place in Xingjiang. Antibodies against KSHV latent antigen ORF73,1ytic antigens KS. 1 and ORF65 are measured by an ELISA-based assay. Chi-square test was performed to analysis the data. In this study,60 out of 199 sera samples （30.6%） were KSHV positive. Via Chi-Square Tests, there was no significantly difference among age, occupation, education levels, marriage statuses, HIV-1 status. There was no overall significant KSHV seroprevalences difference among taking drug by injection,by mouth, and ones by mouth and injection both, duration of drug using, sharing needle. Our data implicate KSHV seroprevalences was higer and KSHV was common among these in this population.

关 键 词：卡波氏肉瘤相关病疱疹毒 吸毒人群 血清流行病学 

分 类 号：R512.91[医药卫生—内科学]