代谢综合征及其组分聚集对肺功能的影响  

Effect of Metabolic Syndrome(MS)and Aggregations of MS Components on Lung Function

作　　者：潘锋丰[1] 杨敬业[1] 章晓燕[1] 李胜前[1] 孙小康[1] 

机构地区：[1]上海市第六人民医院,上海200233

出　　处：《中国医药导刊》2010年第1期14-15,18,共3页Chinese Journal of Medicinal Guide

摘　　要：目的:探讨代谢综合征(metabolic syndrome,MS)患者肺功能的变化以及代谢综合征组分的聚集对肺功能的影响。方法:检测并比较43例代谢综合征(MS)患者和61例非代谢综合征(non-metabolic syndrome,non-MS)患者的肺功能,进一步根据MS定义中代谢异常组分的累加评分(0～4分)分为5组,比较各组间肺功能变化。结果:MS组肺活量(FVC)、1秒钟用力呼气容积(FEV1)、最大通气量(MVV)、肺一氧化碳弥散量(DLco)均明显低于non-MS组(P<0.01)。随着代谢综合征组分的增加,FVC、FEV1、MVV、DLco均有下降。结论:MS患者较non-MS患者有明显的肺功能减退,且随着代谢异常的累积,肺功能的损害也有所增加。Objective：To study the metabolic syndrome （MS） patients with changes in lung function, and assess the effect of aggregations of MS components on lung function. Methods：Detect and compare the 43 cases of metabolic syndro me （MS） and 61 eases of non-metabolic syndrome （non-MS} in patients with lung function. Patients were categorized into 0 to 5 groups according to component number of metabolic syndrome （MS） .the lung function were compared among groups. Results：MS group of vital capacity（FVC）, forced expiratory volume in first second（FEV1） . maximal voluntary ventilation（MVV）, and diffusion capacity for carbon monoxide of lung（DLco） were significantly decreased than non-MS group（ P 〈 0. 01）. As the metabolic disorder score increased ,FVC,FEV1,MVV, DLco were all decreased. Conclusions：MS patients have significantly decreased lung function than non-MS patients. The degree of metabolic disorder clustering is strongly related to the lesion of tung function.

关 键 词：代谢综合抓 高血糖 高血压 高血脂 肥胖 肺功能 

分 类 号：R589[医药卫生—内分泌]