用光谱方法检测肌氧饱和度实现不同人群运动功能的评估  

Evaluation of Kinematic Capability of Different Groups by Detecting Oxygen Saturation of Muscle Using Near Infrared Spectroscopy

作　　者：李岳[1] 齐贺斌[2] 史济招[2] 腾轶超[1] 丁海曙[1] 

机构地区：[1]清华大学医学院生物医学工程系,北京100084 [2]北京协和医院,北京100730

出　　处：《光谱学与光谱分析》2010年第2期440-443,共4页Spectroscopy and Spectral Analysis

基　　金：国家自然科学基金项目(60578004)资助

摘　　要：基于组织光学原理研发了组织氧饱和度无损检测仪。利用该仪器检测了101名受试者(其中健康锻炼者42人,健康不锻炼者34人,脾虚证患者25人)在进行递增负荷功率自行车运动实验时,股四头肌外侧头的肌氧变化过程。测得的血红蛋白浓度(ctHb)受脂肪等外层组织影响较大,而肌氧饱和度(rSO2)受影响较小。实验结果显示,在运动过程中,随着运动负荷的逐渐增加,骨骼肌中的总血红蛋白浓度逐渐上升,肌氧饱和度逐渐降低;当运动停止后,总血红蛋白浓度和肌氧饱和度都出现快速上升。运动中肌氧饱和度的变化幅度与受试者运动能力有密切关系。利用局部组织氧饱和度这一指标来评价肌肉组织中氧的输送与消耗的平衡点,进而实现了对肌肉组织有氧代谢能力的定量评估。Based on the principles of organizational optics, the noninvasive tissue oxygenation saturation monitor was developed. The monitor was used to continuously monitor the changes in regional oxygen index of the thigh vastus lateralis in 101 volun- teers, who performed an incremental intensity exercise on bicycle ergometer. Among the volunteers, 42 are athletes, 25 are pa- tients whose spleens are asthenie, and the other 34 are controls. Hemoglobin concentration （C1Hb） measured was heavily influ- enced by the thickness of fattiness; however, regional oxygen saturation （rSO2） was influenced much lightly. In the experiment, following increasing exercise intensity of the volunteers, their C1hB increased, while their rSO2 decreased. When the volunteers stopped the exercise, both of their C1Hb and rSO2 increased quickly. The results showed that the regional saturation of oxygen of muscle was closely correlated with physical performance. The changes of regional saturation of oxygen of muscle can be used to evaluate the balance between supply and consumption o{ oxygen, and quantitatively assess the capability of oxidative metabolism in muscles.

关 键 词：近红外光谱 肌肉 氧饱和度 运动负荷 

分 类 号：R318.5[医药卫生—生物医学工程]