3种清洁手术预防使用抗菌药物调查分析  

Perioperative Prophylactic Use of Antibacterials for Three Types of Clean Surgery

作　　者：鲁薇[1] 黄万青[1] 赵晓娟[1] 张少华[1] 

机构地区：[1]马鞍山市人民医院药事科,安徽马鞍山243000

出　　处：《中华医院感染学杂志》2010年第4期539-541,共3页Chinese Journal of Nosocomiology

摘　　要：目的了解医院3种清洁手术预防使用抗菌药物的情况并进行合理性分析。方法通过查阅2008年9月的出院病例,对甲状腺、乳腺和疝气3种清洁手术病例进行回顾性调查。结果在调查的38份手术病例中,5例未使用抗菌药物;第一代头孢菌素使用率30.3%,其他抗菌药物使用比例过大;术后24 h停药4例,48 h停药3例,平均用药为4.97 d;单一用药28例,累积2种抗菌药物5例;抗菌药物费用占总药品费用<50.0%者4例,<70.0%者13例。结论3种清洁手术预防使用抗菌药物存在起点过高、疗程过长等现象,应强化医师围手术期预防性应用抗菌药物的合理化意识。OBJECTIVE To know the present situation of perioperative antibiotic prophylaxis in three types of clean surgery and evaluate its rationality. METHODS The usage of perioperative antibiotic prophylaxis in thyroid, mamnalian and hernia surgery was surveyed. RESULTS 05 the 38 cases, 5 cases received no antibacterials treatment. Only 30.3 % of patients used first generation cephalosporin, other antibacterials usage was too high in proportion. The antibacterials stopped in 4 cases 24 h after operation and 3 cases 48 h after operation, the average course of treatment was 4.97 d. A single medication was used in 28 eases, and two kinds of antimicrobials in 5 cases. Antibiotics drugs cost less than 50. 0% of the total cost was in 4 cases, less than 70. 0% in 13 cases. CONCLUSIONS Perioperative prophylactic use of drug for three types of clean surgery in our hospital exist the problems of high proportion of high grade drugs in preventive medication, and the prolonged postoperative use of antibacterials. It is urgent to intensify physicians consciousness about rational perioperative use of antibacterials.

关 键 词：清洁手术 抗菌药物 预防用药 

分 类 号：R978.1[医药卫生—药品]