116例少动鞘氨醇单胞菌的医院感染及耐药特点  

Nosocomial Infection due to Sphingomonas paucimobilis and Its Drug Resistance:An Analysis of 116 Cases

作　　者：来汉江[1] 杨莉俊[1] 周鸿亮[1] 顾保罗[1] 

机构地区：[1]杭州萧山第一人民医院检验科,浙江杭州311201

出　　处：《中华医院感染学杂志》2010年第4期581-583,共3页Chinese Journal of Nosocomiology

摘　　要：目的了解医院少动鞘氨醇单胞菌的医院感染及耐药特点。方法回顾性分析116例患者感染相关因素和药物敏感试验。结果116菌株主要来自于痰液，其次血液和胆汁，依次为74．14％、7．76％、6．90％；标本主要分离于重症监护病房（ICU）和呼吸科患者，占51．69％；药敏试验对氨曲南高度耐药（90．52％），头孢替坦、复方新诺明、环丙沙星耐药高达48．28％～55．17％，氨基糖苷类耐药率较低。结论少动鞘氨醇单胞菌感染菌株对多种抗菌药物有较高的耐药性，针对易感因素采取有效措施减少医院感染。OBJECTIVE To study the Sphingomonas paucirnobilis infection and its resistance to antimicrobial agents. METHODS All of 116 infection cases and drug susceptibility were retrospectively investigated. RESULTS The most common sources of specimens were sputum（74. 14%）, blood（7. 76%） and bile（6. 90%）. 51. 69% infection mainly distributed at ICU and respiratory wards. Sensitivity test result showed that the resistance to aztreonam was high（90.52%）, that to cefotetan, trimethoprim/sulfamethoxazole and ciprofloxacin was high too （48.28%-55.17%）, but to aminoglycosides was the low, and sensitive to imipenem. CONCLUSIONS S. paucimobilis has higher resistance to antimicrobials and we must take prevention management to reduce nosocomial infection.

关 键 词：少动鞘氨醇单胞菌 耐药 医院感染 

分 类 号：R181.32[医药卫生—流行病学]