复方邻苯二甲醛消毒剂性能的试验观察  

EXPERIMENTAL OBSERVATION ON PROPERTIES OF COMPOUND ORTHOPHTHALALDEHYDE DISINFECTANT

作　　者：宋江南[1] 陈贵秋[1] 朱应凯[1] 庄世锋[1] 高琼[1] 李世康[1] 聂焱[1] 

机构地区：[1]湖南省疾病预防控制中心,长沙410005

出　　处：《中国消毒学杂志》2010年第1期17-19,22,共4页Chinese Journal of Disinfection

摘　　要：目的观察一种复方邻苯二甲醛消毒剂的消毒性能。方法用载体定量和定性杀菌试验法,对该复方邻苯二甲醛消毒剂杀菌效果进行检测,用动物实验方法对其毒性作出评价。结果用含5.7 g/L邻苯二甲醛的该复方消毒剂对不锈钢载体上枯草杆菌黑色变种芽孢作用60 min,平均杀灭对数值>5.0;作用120 min,可达到完全杀灭。该复方邻苯二甲醛消毒剂对小鼠急性经口毒性试验LD50值>5000 mg/kg体重,小鼠骨髓嗜多染红细胞结果阴性。该邻苯二甲醛消毒剂原液密封包装,经54℃恒温存放14 d,其含量下降率为8.72%。结论该复方邻苯二甲醛消毒剂对细菌芽孢杀灭效果较好,属于无毒级物质,储存性能稳定。Objective To observe the disinfection property of a compound orthophthalaldehyde disinfectant. Methods Carrier quantitative and qualitative germicidal tests were used to examine the germicidal efficacy of the compound orthoph- thalaldehyde disinfectant. Animal test method was used to evaluate the toxicity. Results The average killing logarithm val- ue of Bacillus subtilis var. niger spores on stainless steel carrier exposed to the disinfectant containing orthophthalaldehyde 5.7 g/L for 60 rain was 〉 5.0 and spores of Bacillus subtilis var. niger on the carrier exposed for 120 min were killed completely. LD50 of the oral acute toxicity of the disinfectant in mice was 〉 5000 mg/kg · bw. The result of mouse bone marrow polychromatic erythrocyte micronucleus test was negative. After storing in air - tight packing at 54℃ constant tem- perature for 14 d, its orthophthaladehyde cantent decreased by 8.72%. Conclusions The compound orthophthalaldehyde disinfectant has good efficacy in killing bacterial spores. It has no toxicity. It is stable during storage.

关 键 词：邻苯二甲醛 杀菌效果 稳定性 毒性 

分 类 号：R187.2[医药卫生—流行病学]