丹槐银屑浓缩丸对小鼠银屑病模型的病理实验研究  

Pathologic Experimental Study of Danhuaiyinxie Concentrated Pill on Mice with Psoriasis

作　　者：王学军[1] 陶以成[2] 刘长发[2] 

机构地区：[1]黑龙江省中医研究院,哈尔滨150036 [2]黑龙江中医药大学,在读博士哈尔滨150040

出　　处：《中国中医急症》2010年第1期104-105,共2页Journal of Emergency in Traditional Chinese Medicine

摘　　要：目的验证丹槐银屑浓缩丸的药效,为其临床应用提供试验依据。方法采用小鼠阴道上皮细胞有丝分裂模型、尾部鳞片表皮模型,观察丹槐银屑浓缩丸对小鼠阴道上皮细胞有丝分裂及尾部鳞片表皮细胞分化的影响。结果丹槐银屑浓缩丸能显著抑制小鼠阴道上皮细胞的有丝分裂,促进小鼠尾部鳞片表皮颗粒层形成。结论丹槐银屑浓缩丸具有抑制银屑病小鼠模型阴道上皮有丝分裂,促使小鼠动物模型尾部鳞片颗粒层形成的作用。Objective： To observe the pharmacodynamic action of Danhuaiyinxie Concentrated Pill in order to support the clinical application of it. Methods： The influences of Danhuaiyinxie Concentrated Pill on caryomitotic vaginal epithelial cell and tail squamous surface cell of mice were observed. Results： Danhuaiyinxie Concentrated Pill could inhibit earyomitotic vaginal epithelial cell and promote the formation of tail squamous surface cell of mice. Conclusion： Danhuaiyinxie Concentrated Pill has certain effect on inhibiting caryomitotic vaginal epithelial cell and promoting the formation of tall squamous surface cell of mice.

关 键 词：丹槐银屑浓缩丸 小鼠阴道上皮细胞有丝分裂模型 小鼠尾部鳞片表皮模型 

分 类 号：R285.5[医药卫生—中药学]