系统性红斑狼疮并发感染的危险因素临床特点及早期诊断  

Infections in systemic lupus erythematosus:risk factors,clinical characteristics and early diagnosis

作　　者：吴晓静[1] 陈楠[1] 

机构地区：[1]上海交通大学医学院附属瑞金医院肾脏科,上海200025

出　　处：《中国实用内科杂志》2010年第2期154-156,共3页Chinese Journal of Practical Internal Medicine

基　　金：上海市重点学科(T0201);上海市卫生局重点学科基金(05Ⅲ001);上海市卫生局重点课题(2003ZD002)

摘　　要：感染是影响系统性红斑狼疮(SLE)患者病死率的重要因素之一,故早期诊断感染并发症能显著改善SLE患者预后。血清C-反应蛋白(CRP)、降钙素原(PCT)有助于鉴别SLE并发感染和SLE活动,血清KL-6有助于鉴别SLE伴发感染和SLE累及肺脏。SLE合并感染的病原体除了最多见的细菌感染外,病毒和真菌感染近几年有上升趋势,需要引起足够重视。Infectious diseases have emerged as one of the leading causes of morbidity and mortality in systemic lupus erythematosus （SLE）patients, so early diagnosis of infectious complication in SLE patients is absolutely beneficial for patients＇ prognosis. C-reactive protein（CRP） and Procalcitonin（PCT） can help to differentiate infections with active SLE in SLE patients. Serum KL-6 can help to distinguish pulmonary involvement of SLE from infections in SLE patient. The most common pathogens for infection in SLE patients are bacteria, but more attention should be paid to viral and fungal infections,which have been on a rise recently.

关 键 词：系统性红斑狼疮 感染 

分 类 号：R5[医药卫生—内科学]