等剂量耐乐品和布比卡因腰麻用于剖宫产的效能比较  

Compare the effects of the same dose of ropivacaine and bupivacaine for spine anesthesia in the patients undergoing caesarean section

作　　者：劳巧仪 杨水根 黄宜发 

机构地区：[1]开平市中医院麻醉科,529300

出　　处：《中国实用医药》2010年第3期27-28,共2页China Practical Medicine

摘　　要：目的比较相同剂量的耐乐品和布比卡因蛛网膜下腔阻滞用于剖宫产的效能,以探讨剖宫产的最佳局麻药。方法将120例ASAⅠ-Ⅱ级择期行剖宫产患者,随机分成二组,用0.75%耐乐品和布比卡因各1.8ml,分别用脑脊液0.7ml配成等比重溶液,用25G蛛网膜下腔阻滞穿刺针,于L3～4间隙穿刺,在15s内缓慢将2.5ml药液注入蛛网膜下腔,比较两组感觉、运动阻滞的起效和恢复时间的异同点。结果在感觉阻滞起效时间上,耐乐品>布比卡因;在恢复时间和最大阻滞时间上耐乐品>布比卡因;在最高麻醉平面上布比卡因>耐乐品;在运动阻滞起效时间上,耐乐品>布比卡因;在最大运动阻滞时间和恢复时间上布比卡因>耐乐品;在镇痛效果及肌松上布比卡因>耐乐品;在低血压、呼吸困难等不良反应上,布比卡因>耐乐品。结论耐乐品具有布比卡因的优点,而且能克服布比卡因的缺点,是蛛网膜下腔阻滞行剖宫产更为理想的局麻药。Objective To compare the effects of the same dose of Ropivacaine and Bnpivacaine for spine anesthesia in the patients undergoing caesarean section. Methods Total of 120 women （ ASA Ⅰ or Ⅱ ） who would be given caesarean section were at random divided into two groups in order to receive one of the following isobaric intratheeal solutions （containing ropivacaine and bupivaeaine, respectively） with cerebrospinal fluid as diluent. The difference of sensory block, motor block and recovery was compared. Results There were differences among the two groups in onset time, block height and the longest duration time of sensory block. As for onset time, block height, and the quality of analgesia and muscular relaxation, various ranks were listed as follow： ropivaeaine 〉 bupivacaine, bupivacaine 〉 ropivaeaine, and bupivaeaine 〉 ropivaeaine. Conclusion Ropivacaine might be the appropriate choice when caesarean section is performed.

关 键 词：罗哌卡因 布比卡因 剖宫产 蛛网膜下腔阻滞 

分 类 号：R614[医药卫生—麻醉学]