高效液相色谱法检测单基发射药中的二苯胺  

Determination of Diphenylamine in Single-base Propellant by High-performance Liquid Chromatography

作　　者：梁晓东[1] 陈智勇[1] 乔敬林[1] 孙力[1] 李林[1] 骆传环[2] 

机构地区：[1]中国人民解放军66294部队 [2]军事医学科学院放射与辐射医学研究所

出　　处：《科学技术与工程》2010年第5期1211-1214,共4页Science Technology and Engineering

摘　　要：采用不同的萃取条件对发射药进行处理,检测对二苯胺的萃取情况。考察不同试验条件下单基发射药中二苯胺的液相色谱行为,建立了二苯胺的HPLC测定方法。选用VenusilMP-C18色谱柱(250mm×4.6mm,5μm),用甲醇和水为流动相(80:20),流速为1mL/min,检测波长280nm。该方法的线性范围为(0.05—100)μg/mL,线性回归方程为:Y=708956X,相关系数r=0.9998。该方法最低检测浓度为0.05μg/mL。回收率在98%-102%之间,相对标准偏差均小于2%。说明方法简单,操作简便,结果准确可靠,可用于单基发射药中二苯胺的含量测定和控制。To establish high-performance liquid chromatography （HPLC） method determination of content of diphenylamine （DPA） in propellant. Venusil MP-C18 column （250 mm× 4.6 mm,5 μm） with methanol-water （80：20） as mobile phase, the flow rate was 1 mL/min;the ultraviolet detection wavelength was 280nm. There was a good linear relationship within （0.04--80） μg/mL, regression equation was Y = 708 956 X , r = 0. 999 8. The method is validation, and the stability tests under various conditions are performed. The reproducibility and precision of method are good （RSD = 0. 64% ）. The lowest detectable concentration of diphenylamine is 0.05μg/mL. The recoveries are 99% - 101% and the relative standard deviation is less than 1%. It is conclusied that the method proposed for content of diphenylamine by HPLC is simple, accurate, specific and could be used in quality control diphenylamine.

关 键 词：二苯胺 发射药 高效液相色谱法 化学安定性 

分 类 号：O657.72[理学—分析化学]