Efficient Synthesis of 3,5,6,8-Tetrahydro-4H-thiopyrano[4′,3′:4,5]· thieno[2,3-d]pyrimidin-4-ones via an Iminophosphorane  

作　　者：LI Wen-jing LIU Min FENG Ling-ling DING Ming-wu 

机构地区：[1]Key Laboratory of Pesticide ＆ Chemical Biology of Ministry of Education, Central China Normal University, Wuhan 430079, P. R. China

出　　处：《Chemical Research in Chinese Universities》2010年第1期60-65,共6页高等学校化学研究（英文版）

基　　金：Supported by the National Natural Science Foundation of China(No.20772041);the Key Project of Chinese Ministry of Education(No.107082)

摘　　要：3,5,6,8-Tetrahydro-4H-thiopyrano[4＇,3＇：4,5]thieno[2,3-d]pyrimidin-4-ones（7） were synthesized via the base catalytic reactions of amines or phenols with carbodiimides（5）, which were obtained from the aza-Wittig reac tions of iminophosphoranes（4） with aromatic isocyanates.3,5,6,8-Tetrahydro-4H-thiopyrano[4＇,3＇：4,5]thieno[2,3-d]pyrimidin-4-ones（7） were synthesized via the base catalytic reactions of amines or phenols with carbodiimides（5）, which were obtained from the aza-Wittig reac tions of iminophosphoranes（4） with aromatic isocyanates.

关 键 词：3 5 6 8-Tetrahydro-4H-thiopyrano[4＇ 3＇：4 5]thieno[2 3-d]pyrimidin-4-one Aza-Wittig reaction Carbodii- mide ISOCYANATE 

分 类 号：TQ457.29[化学工程—农药化工] TB333[一般工业技术—材料科学与工程]