芪苈强心胶囊对心力衰竭的干预作用研究  被引量:4

The clinical study on Qiliqiangxin capsule interference with heart failure

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作  者:李伟扬[1] 徐晶[1] 王强[3] 李秋丽[4] 姜锋[1] 楼南芳[2] 

机构地区:[1]牡丹江医学院红旗医院心内科,牡丹江157011 [2]牡丹江医学院红旗医院肾内科,牡丹江157011 [3]牡丹江医学院附属二院心内科,牡丹江157011 [4]牡丹江医学院医学影像学系,牡丹江157011

出  处:《国际中医中药杂志》2010年第1期18-19,共2页International Journal of Traditional Chinese Medicine

基  金:黑龙江省卫生厅资助课题(项目编号:2007-032)

摘  要:目的观察芪苈强心胶囊联合常规西药对慢性心力衰竭(congestive heart failure,CHF)干预作用的临床疗效。方法将61例CHF患者采用随机数字表法分为两组,对照组31例采用常规抗心衰治疗,治疗组30例在对照组治疗基础上加服芪苈强心胶囊,2周为1个疗程,共治疗2个疗程。比较两组临床疗效及治疗前后体重、尿量、6min步行距离(6MWD)、心电图、心脏超声等检查。结果4周后,治疗组心功能改善总有效率为93.33%、对照组为74.19%,两组比较差异有统计学意义(X^2=4.07985,P〈0.05);治疗组左室射血分数(LVEF)提高率为(16±4)%,对照组为(11±3)%,两组比较差异有统计学意义(t=5.509,P〈0.001)。结论芪苈强心胶囊为主治疗CHF患者,可有效改善心功能,提高LVEF,改善临床症状,提高生活质量。Objective To observe the clinical role of Qiliqiangxin capsules uniting conventional western medicine interfering with chronic heart failure(CHF). Methods 61 cases of CHF were randomly recruited into a control group (31 cases ) and a treatment group (30 cases). The control group was treated with conventional anti-heart failure treatment, and the treatment group was added Qiliqiangxin capsules on the treatment of the control group. After having been treated for 2 courses (four weeks), such indexes as clinical efficacy, body weight, urine volume, 6 min walking distance(6MWD), electrocardiogram, and cardiac ultrasound were measured for both groups. Results The overall efficiency of cardiac function was 93.33% for the treatment group and 74.19% for the control group. There was significant difference between the two groups (X^2=4.07985, P〈0.05 ) . The enhance rate of left ventricular ejection fraction (LVEF) was (16±4) % in the treatment group as compared to ( 11±3 ) % in the control group, also showing statistical difference between the two groups ( t= 5.509, P 〈0.001 ) . Conclusion Qiliqiangxin capsules combined with conventional western medicine could effectively improve the cardiac fimction, LVEF, clinical symptoms, and quality of life in the patients with chronic heart failure.

关 键 词:芪苈强心胶囊 心力衰竭 干预作用 

分 类 号:R541.6[医药卫生—心血管疾病] R259.416[医药卫生—内科学]

 

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