南宁市首例人感染高致病性禽流感病例的流行病学调查  

Epidemiologic survey of the first case infected with highly pathogenic avian influenza virus(H5N1) in Nanning

作　　者：谭毅[1] 莫兆军[1] 杨进业[1] 李海[1] 莫建军[1] 陈敏玫[1] 闭福银[1] 莫毅[1] 康宁[1] 周开姣[1] 

机构地区：[1]广西壮族自治区疾病预防控制中心病毒科,广西南宁530028

出　　处：《中华疾病控制杂志》2010年第2期112-115,共4页Chinese Journal of Disease Control & Prevention

基　　金：广西科学基金(桂科自0832197)

摘　　要：目的对南宁市首例人感染高致病性禽流感病例进行流行病学调查分析,为进一步科学防控人禽流感提供依据。方法采用现场流行病学调查方法对病例和密切接触者进行个案调查,采用RT-PCR方法对病例呼吸道标本进行人感染高致病性禽流感病毒(H5N1)检测。结果确诊南宁市首例人感染高致病性禽流感病例,该病例经抢救无效死亡,病例有明确病死禽接触史。在采取病例隔离治疗、医护人员个人防护、密切接触者医学观察、消毒等综合控制措施后,疫情得到有效控制,密切接触者中未出现异常情况,未出现二代病例。结论需加强人禽流感疫情监测,加强医务人员培训,预防疫情发生。Objective To analyze epidemiologic investigation of the first case infected with highly pathogenic avian influenza virus （HSN1） in Nanning and provide scientific evidence for further prevention and control of avian influenza. Methods Field epidemiology was conducted for case investigation. Respiratory specimens from the patients were tested by reverse transcriptase （RT） PCR for the presence of HSN1 virus. Results The first case infected with highly pathogenic avian influenza virus （HSN1） in Nanning was finally diagnosed. The patient was dead due to invalid salvage and history of exposure to infected poultry was confirmed. The outbreak was effectively controlled after comprehensive intervention measure were taken, which includes case isolation and treatment, individual shield for staff, medical observation of intimate contactors. Abnormal occurrence and secondary cases was not found in person contactors. Conclusions Surveillance and Staff training were urgently necessary for avian influenza prevention and control.

关 键 词：禽流感 感染 流行病学 

分 类 号：R511.7[医药卫生—内科学]