阜阳市1958-2007年肾综合征出血热流行特征及相关因素分析  

Analysis about epidemiological characteristics and factors of hemorrhagic fever with renal syndrome during 1958 to 2007 in Fuyang

作　　者：朱理业[1] 万俊峰[1] 丁振涛[1] 刘奇泉[1] 见海晖[1] 田亚贞[1] 蒋(弓叟) 

机构地区：[1]阜阳市疾病预防控制中心,安徽阜阳236030

出　　处：《中华疾病控制杂志》2010年第1期55-59,共5页Chinese Journal of Disease Control & Prevention

摘　　要：目的了解阜阳市肾综合症出血热(hemorrhagic fever with renal syndrome,HFRS)流行特征及流行因素,为制定防制措施提供科学依据。方法对1958年以来的人间及1984年以来的鼠间疫情监测资料进行描述性分析,利用圆形分布,计算发病高峰日期;同时对发病率与带毒指数进行相关性分析。结果1958-2007年全市共报告HFRS病例40002例,死亡2381例,年平均发病率为11.99/10万,病死率为5.95%。各县市区均有病例,颍上县最多(占40.30%),病死率以界首市最高(33.24%)。50年来共呈现4次发病高峰,20世纪80、90年代维持在较高的流行强度。各月均有发病,主要集中在11月至次年1月份,发病高峰日为12月13日。室内和野外鼠密度分别为9.84%和7.91%,带毒率分别为9.21%和6.99%。1984-2007年的鼠带毒指数和人群发病率的相关系数为r=0.58。室内的优势鼠种在2000年前为褐家鼠,2000年后为小家鼠;野外的优势鼠种一直为黑线姬鼠。结论阜阳市HFRS疫源地普遍存在,鼠密度及带毒率的高低直接影响到人群发病,应加强鼠间疫情监测。Objective To investigate the epidemiological characteristics and factors of hemorrhagic fever with renal syndrome （HFRS） during 1958 to 2007 in Fuyang. Methods Descriptive study method was used to analyze the epidemiological characteristics of hemorrhagic fever with renal syndrome. The incidence peak of hemorrhagic fever with renal syndrome was computed by using rotundity distribu- tion. The correlation was analyzed between incidence and virus index by Pearson correlation. Results 40 002 HFRS cases was reported during 1958 to 2007 in Fuyang and 2381 cases were dead. The average incidence and fatality rate of HFRS were 11.99 per 100 thousand and 5.95 percent respectively. Eight counties all had cases. Yingshang county had the highest cases and Jieshou city had the highest fatality rate. Since 1958, there＇ re 4 incidence peak in Fuyang. The period of high incidence was during November to January of next year and the peak of incidence rate was on December 13. Indoor density and field density of mouse were 9.84 percent and 7.91 percent respectively. Virus rate of indoor and field of mouse were 9.21 percent and 6.99 percent respectively. During 1984 to 2007, the correlation coefficient between virus index and incidence was 0.58. In room brown mouse was the most before 2000, but then house mouse become the most. In open country heavy line Japanese fieldrnouse is the most mouse all the time. Conclusions In Fuyang, the focus of HFRS is exist widely. Density and virus rate of mouse will directly affect the incidence. So surveillance among mouse should be strengthened.

关 键 词：肾综合征出血热 流行病学研究特征(主题) 流行病学因素 带毒指数 

分 类 号：R512.81[医药卫生—内科学]