抗生素相关性腹泻的临床分析及治疗  

Clinical Analysis and Treatment for Antibiotic Associated Diarrhea

作　　者：严勤[1] 齐正波[1] 李连茂[1] 

机构地区：[1]中航工业哈尔滨242医院感染性疾病科,哈尔滨市150066

出　　处：《中国药房》2010年第6期523-525,共3页China Pharmacy

摘　　要：目的:分析抗生素相关性腹泻(AAD)的发病特点,为临床制定有效的预防措施提供依据。方法:回顾性分析我院2006～2008年内科住院接受抗生素治疗的488份病历,对其中42份AAD的临床表现、抗生素使用情况以及治疗和转归等进行统计分析。结果:AAD的发病率为8.6%。应用抗生素时间超过7d、应用广谱抗生素、联合应用2种以上抗生素、年龄大于70岁等患AAD的发病率高于对照组(P<0.05)。结论:合理应用抗生素是预防AAD的关键。OBJECTIVE： To observe the clinical character of antibiotic associated diarrhea（AAD）in order to provide reference for prevention measures. METHODS： Retrospective analysis was applied to analyze 488 inpatients treated with antibiotics in our hospital from 2006 to 2008, of which 42 AAD cases were analyzed in terms of clinical manifestation,utilization of antibiotics, therapy and prognosis, etc. RESULTS： The incidence of AAD arrived at 8.6%. The reason that incidence of AAD was higher than that of control group was above 7 days of antibiotics treatment, broad-spectrum antibiotic, more than two kinds of antibiotics and over 70 years old. CONCLUSION ： The key point of preventing AAD is rational use of antibiotics.

关 键 词：抗生素相关性腹泻 艰难梭状芽孢杆菌 合理用药 

分 类 号：R969.3[医药卫生—药理学] R978.1[医药卫生—药学]