仙灵骨葆胶囊治疗骨质疏松症41例疗效观察  

Clinical observation of Xianling Gubao capsule on osteoporosis

作　　者：龙友余[1] 王英[1] 王旭凯[1] 

机构地区：[1]天津中医药大学第二附属医院急诊科,天津300150

出　　处：《河北中医》2009年第10期1536-1537,共2页Hebei Journal of Traditional Chinese Medicine

摘　　要：目的观察仙灵骨葆胶囊治疗骨质疏松症（OP）的临床疗效。方法将83例OP患者随机分为2组,治疗组41例给予仙灵骨葆胶囊治疗,对照组42例给予骨疏康颗粒治疗。治疗6周后,观察2组临床疗效,治疗前后检测患者腰椎（L2-4）、股骨颈骨密度（BMD）和血钙（Ca）、磷（P）、碱性磷酸酶（ALP）。结果治疗组总有效率95.1%,对照组为71.4%,2组总有效率比较差异有统计学意义（P〈0.05）,治疗组优于对照组。治疗组治疗前后腰椎BMD比较差异有统计学意义（P〈0.05）,治疗后优于治疗前。且与对照组治疗后比较差异有统计学意义（P〈0.05）。治疗组治疗前后ALP比较差异有统计学意义（P〈0.05）,治疗后优于治疗前。2组治疗后血Ca、P、ALP比较差异无统计学意义（P〉0.05）。结论仙灵骨葆胶囊具有抑制骨吸收、降低骨转换、提高骨量的作用,是治疗OP的有效药物。Objective To discuss the curative effect of Xianling Gubao capsule in treating osteoporosis. Methods 83 patients with osteoporosis were randomly divided into two groups. Cases in the treatment group （ n = 41 ） were treated by Xianling Gubao capsule. And patients in the control group （ n =42） received Gushukang. The course was six weeks in two groups. BMD of lumbar （ L2 -4 ） and collum femoris of patients, Ca, P and ALP in blood were detected before and after treatment for evaluation of effect. Results The total effective rate in treatment group （95.1% ） was superior to that in control group （71.4% , P 〈 0. 05 ）. BMD of lumbar after treatment was superior to that before treatment in treatment group （ P 〈 0.05 ）. And BMD of lumbar in treatment group was superior to that in control group after treatment （ P 〈 0. 05 ）. There was no significant difference in calcium, phosphorus, and alkaline phosphatase between two groups after treatment, but the alkaline phosphatase in treatment group decreased significantly during treatment （ P 〈 0.05 ）. Conclusion Xianling Gubao capsule is effective drug in treating osteoporosis.

关 键 词：骨质疏松 中药疗法 胶囊 

分 类 号：R681.405.31[医药卫生—骨科学] R283.65[医药卫生—外科学]