慢性阻塞性肺疾病急性加重期C反应蛋白变化的临床意义  

Clinical significance of The changes of C-reactive protein in acute phase of chronic obstructive pulmonary disease

作　　者：李建华[1] 林勇[2] 

机构地区：[1]邹城市兖矿集团南屯矿医院内科,山东省邹城273515 [2]济宁市第一人民医院呼吸内科

出　　处：《中国基层医药》2009年第11期1969-1970,共2页Chinese Journal of Primary Medicine and Pharmacy

摘　　要：目的探讨慢性阻塞性肺疾病急性加重期（AECOPDj患者C反应蛋白（CRP）变化及临床意义。方法选择AECOPD患者96例，观察抗生素治疗前后CRP、指标的变化。结果AECOPDCRP阳性率为85．40％。治疗后CRP显著下降，其治疗前后的差异有统计学意义（P〈0．01）。结论CRP可作为AECOPD的敏感指标，对肺部感染严重程度和反映抗生素疗效具有重要意义。Objective To investigate the changes of CRP in diagnosis of the acute exacerbation of COPD and its significance. Method CRP and WBC were measured both when the patients just before and after the treatment with effective antibiotics to compare their change. Results The positive rate of CRP is 85.40%, and the difference was obvious （ P 〈 0. 01 ）. At the same time, the CRP＇s difference between before and after the use of antibiotics was also obvious （ P 〈 0. 01 ）. Conclusion CRP is a sensitive and specific index to the acute exacerbation of COPD, and is helpful to discover this acute disease early as well as a good guide to estimate the serious of pneumonia sand to respond the efl3cacy of antibiotics.

关 键 词：C反应蛋白 肺疾病 慢性阻塞性 

分 类 号：R563[医药卫生—呼吸系统] R541.4[医药卫生—内科学]