代谢综合征发病机制研究进展  

Research Progress in Pathogenesis of Metabolic Syndrome

作　　者：陈晓蕾[1] 周弘[1] 

机构地区：[1]上海大学校医院,上海200444

出　　处：《医学综述》2010年第3期431-433,共3页Medical Recapitulate

摘　　要：代谢综合征(MS)是多种代谢危险因素在同一个体内集结的病理状态。其病因和发病机制尚未完全阐明。近年来的研究认为MS是复杂的遗传因素及环境因素相互作用的结果。其中,腹型肥胖、慢性炎症及胰岛素抵抗及其相互作用在MS的发病机制中起了重要作用。尤其是炎症病因学理论备受关注,而肥胖、炎症与胰岛素抵抗之间的关系成为研究热点。Metabolic syndrome is a complex disorder of several metabolic risk factors ,which is in the same body. The pathogenesis of MS has not been fully clarified. Recent studies suggest that MS is a complex interaction of genetic factors and environmental factors results. Of these, abdominal obesity, chronic inflammation and insulin resistance and their interactions play a key role in the pathogenesis of MS. In particular the theory of the inflammation cause is concerned, and the relation between obesity, inflammtion and insulin resistance is the hot spots in the study.

关 键 词：代谢综合征 肥胖 炎症 胰岛素抵抗 

分 类 号：R589.2[医药卫生—内分泌]