蒺藜对过度训练大鼠运动能力及内分泌免疫机能的影响  

Effects of Tribulus Terrestris on Exercise Ability,Endocrine and Immune Functions of Over-Trained Rats

作　　者：王晓慧[1] 孙婧瑜[1] 曲静[1] 游盛中[1] 杨文吉[1] 

机构地区：[1]上海体育学院运动科学学院,上海200438

出　　处：《上海体育学院学报》2010年第1期46-49,共4页Journal of Shanghai University of Sport

基　　金：上海市教委创新项目(09YZ303)

摘　　要：目的:观察蒺藜对过度训练大鼠运动能力及内分泌免疫机能的影响。方法:30只雄性健康SD大鼠随机分为安静对照组、过度训练组和蒺藜+过度训练组,后两组大鼠进行6周递增负荷的跑台运动,其中蒺藜+过度训练组灌胃服用蒺藜,其余两组补充等量生理盐水。于第6周末测定过度训练组和蒺藜+过度训练组大鼠一次力竭运动时间,第7周周一检测3组大鼠外周血中部分内分泌激素和免疫指标的变化。结果:与过度训练组相比,蒺藜+过度训练组大鼠一次力竭运动的时间显著提高,表明蒺藜能提高大鼠的运动能力;与过度训练组相比,蒺藜+过度训练组大鼠外周血睾酮水平、T/C比值显著增加,且超过安静对照组的水平,这可能是蒺藜提高运动能力的机制之一;与过度训练组大鼠相比,补充蒺藜能完全逆转过度运动所致的CD8+增加、CD4+/CD8+的降低、NK细胞的减少,以及部分逆转CD3+的减少。结论:蒺藜能提高大鼠的运动能力,这可能与其增加睾酮水平和T/C比值有关;蒺藜对过度训练所致的受抑免疫功能具有改善作用。Purpose： The study aims to investigate the effects of supplementation of Tribulus Terrestris on exercise ability and endocrine and immune functions of over-trained rats. Methods： Thirty SD rats are randomly divided into three groups, the silent control group, over-trained group and over-trained ＋ Tribulus terrestris group. The last two groups are trained for six weeks on a motor driven treadmill with increasing load. The over-trained ＋ Tribulus terrestris group are made to take Tribulus terrestris, while the other two groups take the same amount of saline. The time for one exhaustive exercise is measured for the over-trained group and the over-trained ＋ Tribulus terrestris group at the end of the sixth week and on Monday of the seventh week the changes are measured of some indexes of endocrine and immune systems of the peripheral blood of the third group. Results： Compared with the over-trained group, the time used for one exhaustive exercise in Tribulus terrestris group significantly increased, indicating that Tribulus terrestris can promote the exercise ability of rats. Compared with over-trained group, the peripheral blood testosterone concentration and the T/C ratio increased remarkably in the Tribulus terrestris group, even surpassing the level of the control group, which may be one of the mechanics Tribulus terrestris strengthens exercise capability. Compared with the over- trained group, supplement of Tribulus terrestris can totally reverse the increase of CD8＋, the reduction of CD4 ＋/CD8＋ and the decrease of NK cells induced by over exercises and partly reverse the decrease of CD3 ＋. Conclusions： Tribulus terrestds can enhance the exercise ability of rats, which may be correlated with the increase of testosterone and T/C ratio. At the same time, Tribulus terrestris could also improve the suppressed immune functions caused by over-training.

关 键 词：蒺藜 过度训练 运动能力 睾酮 CD3+细胞 CD4+/CD8+ 大鼠 

分 类 号：G804.2[文化科学—运动人体科学]