盐酸小檗碱与门冬酸钾镁联合治疗肺心病心律失常60例  

Observation on Effect of Berberine and Potassium Magnesium Aspartate for Treating Chronic Pulmonary Heart Disease Complicated by Arrhythmia in 60 Cases

作　　者：修勇[1] 王秀梅[1] 

机构地区：[1]山东省高密市人民医院,山东潍坊261500

出　　处：《中国药业》2010年第5期52-53,共2页China Pharmaceuticals

摘　　要：目的观察盐酸小檗碱与门冬酸钾镁联合治疗慢性肺心病急性发作期并发心律失常的疗效。方法治疗组予盐酸小檗碱0.2g,口服,4次/d;门冬酸钾镁2片(300mg),口服,3次/d。对照组予10%葡萄糖注射液500mL、门冬酸钾镁注射液20mL、胰岛素12U静脉滴注,1次/d。两组均以1周为1个疗程。结果治疗组60例中,治愈38例,好转16例,无效6例,总有效率为90.00%;对照组64例中,治愈12例,好转22例,无效30例,总有效率为53.12%。结论盐酸小檗碱与门冬酸钾镁联合治疗慢性肺心病急性发作期并发心律失常安全、有效。Objective To observe the effect of berberine and potassium magnesium aspartate for treating acute attack of chronic pulmonary heart disease complicated by arrhythmia. Methods The treatment group was orally given with berberine 0.2 g, 4 times per day, and potassium and magnesium aspartate 300 mg （2 tablets）, 3 times per day. In the control group, the patients were treated with 10% glucose solution 500 mL, potassium magnesium aspartate 20 mL, insulin 12 U, by intravenous drip once per day. The treatment course in both groups was one week. Results Among 60 cases in the treatment group, 38 cases were cured, 16 got better and 6 ineffective with the total effective rate of 90. 00%, while among 64 cases in the control group, 12 were cured, 22 got better and 30 ineffective with the total effective rate of 53.12%. Conclusion Berberine and potassium magnesium aspartate for treating acute attack of chronic pulmonary heart disease complicated by arrhythmia is effective and safe.

关 键 词：盐酸小檗碱 门冬酸钾镁 心律失常 肺心病 

分 类 号：R969.4[医药卫生—药理学] R972[医药卫生—药学]