西归对动物消化道功能的影响  

Effect of Xigui on the Gastrointestinal Function of Animals

作　　者：张龙[1] 尹兴章[1] 叶妙萍[1] 徐关丽[1] 郭冲生[1] 方春生[2] 

机构地区：[1]大理学院药学院,云南大理671000 [2]大理学院药学院药理实验室,云南大理671000

出　　处：《云南中医中药杂志》2010年第2期48-49,共2页Yunnan Journal of Traditional Chinese Medicine and Materia Medica

基　　金：大理学院大学基金项目(编号:08DXS013)

摘　　要：目的:研究西归对动物消化道运动功能的影响。方法:采用胃排空,肠推进和离体肠肌实验法研究西归对消化道运动功能的影响。结果:西归对小鼠胃排空有一定的抑制作用,但与正常组相比无显著性差异;高剂量对小鼠肠推进具有抑制作用;对豚鼠离体回肠肌的兴奋具有抑制作用,特别是对乙酰胆碱,组胺,氯化钡引起的豚鼠离体回肠肌的兴奋有显著抑制作用。结论:西归对动物消化道运动功能有抑制作用。Objective:To study the effect of Xigui on the gastrointestinal function of animals.Methods:The methods of gastric emptying,intestinal propulsion and intestinal muscle in vitro were used to determine the influence of Xigui on the gastrointestinal motor function.Results:Xigui showed certain inhibition on the gastric emptying of mice,but had no significant difference when comparing with the normal group.Xigui also showed certain inhibition on the intestinal propulsion of the mice,with its effect increasing with the increase of dose.Xigui had an inhibitive effect on the isolated ileum muscle excitement of guinea pig,especially on the excitement induced by acetylcholine,histamine and barium chloride.Conclusion: Xigui has an inhibition on the gastrointestinal motor function of the animals.

关 键 词：西归 胃排空 肠推进 离体回肠平滑肌 

分 类 号：R285[医药卫生—中药学]