波强度新参数的临床应用  

Application of MWI—a new parameter of wave intensity

作　　者：罗向红[1] 李朝军[2] 曹铁生[1] 段云友[1] 刘杰[1] 

机构地区：[1]第四军医大学唐都医院超声科,陕西西安710038 [2]百胜(深圳)医疗设备有限公司,北京100028

出　　处：《中国医学影像技术》2010年第1期60-62,共3页Chinese Journal of Medical Imaging Technology

基　　金：国家自然科学基金(30770783)

摘　　要：目的应用波强(WI)分析法探讨正常人冷加压实验前后颈总动脉血流平均波强(MWI)、收缩早期瞬时波强(W1)和收缩晚期瞬时波强(W2)在评价颈总动脉功能的可行性。方法健康志愿者24名。应用WI分析法观察记录静息状态下、冷加压后右侧颈总动脉的W1、W2及颈总动脉血流参数,并计算颈总动脉内径百分变化率、血流MWI。绘制W1、W2和MWI的受试者工作特征曲线(ROC),比较三者的检验效能。结果与试验前相比,颈总动脉内径百分变化率与W1均显著减低,MWI与W2显著增加(P<0.05)。MWI、W1和W2的ROC曲线下面积分别为0.858、0.731和0.698,三者间差异无统计学意义(P>0.05)。结论通过常规血流动力学参数计算血流MWI可评价颈总动脉功能。Objective To investigate the feasibility of mean wave intensity（MWI）,W1 and W2 in assessing the function of common carotid artery（CCA）before and after cold presser test with wave intensity analysis.Methods Twenty-four healthy subjects were enrolled.The W1,W2,and other parameters of blood flow in resting,before and after cold presser test of CCA,the inner diameter different rate and MWI of blood flow were calculated respectively.The receiver operation characteristic（ROC）curves were drawn,and of the effectiveness of MWI,W1 and W2 was compared.Results The different rate of diameters and W1 decreased significantly when subjects underwent cold presser test（P 〈0.05）,but MWI and W2 increased significantly（P〉 0.05）.The area under ROC curves was 0.858,0.731 and 0.698,corresponding to MWI,W1 and W2（P〈 0.05）.Conclusion The function of CCA can be evaluated with MWI calculated from conventional parameters.

关 键 词：颈总动脉 冷加压试验 平均波强 波强分析 

分 类 号：R331.33[医药卫生—人体生理学] R445.1[医药卫生—基础医学]