腕关节滑膜厚度和动脉阻力指数评价类风湿性关节炎的活动期  

Synovial membrane thickness and arterial resistance index of wrist in assessing the activity of rheumatoid arthritis

作　　者：朱瑾[1] 张文云[1] 房勤茂[1] 殷春霞[1] 甄景琴[1] 邓荷萍[1] 

机构地区：[1]河北医科大学第三医院超声科,河北石家庄050051

出　　处：《中国医学影像技术》2010年第1期124-126,共3页Chinese Journal of Medical Imaging Technology

基　　金：河北省科技厅科技攻关项目(06276102D-88)

摘　　要：目的评价腕关节滑膜厚度和动脉阻力指数(RI)对类风湿性关节炎(RA)活动期及非活动期的鉴别能力。方法选择临床确诊RA患者92例行高频超声检查,分别测量活动期和非活动期RA患者腕关节滑膜内动脉的RI值及滑膜最大厚度。结果92例RA患者,腕关节滑膜增厚者75例。CDFI显示67例RA患者腕关节滑膜内可探测到血流信号,并可测量动脉RI值;其中活动期31例,非活动期36例。67例RA患者腕关节滑膜厚度为(2.97±1.49)mm,滑膜内动脉的RI值为(0.74±0.17)。与非活动期RA患者相比,活动期RA患者腕关节滑膜内动脉的RI值显著降低(P<0.001),但滑膜厚度差异无统计学意义。结论采用高频超声测量的RA患者腕关节滑膜内动脉RI值可作为临床反映RA滑膜炎性病变的一个客观指标,不能单纯依据滑膜厚度评价RA病变的炎性程度。Objective To assess the value of thickness and arterial resistive index（RI）of wrist synovium in differentiation from activity to non-activity of rheumatoid arthritis（RA）.Methods Ninety-two clinically confirmed RA patients underwent high frequency ultrasonography.Maximum thickness and arterial RI of the wrist synovium were measured in active and nonactive stage.Results Thickened synovium was found in 75 of 92 patients.Color signal in the synovium was detected and then RI was measured in 67 patients,including 31 in active stage and 36 in nonactive stage.The wrist synovium thickness of 67 patients was（2.97±1.49）mm and arterial RI was 0.74±0.17.RI decreased significantly in patients in active stage compared with that in nonactive stage（P 〈0.001）.Conclusion Arterial RI measurement with high frequency ultrasonography may be served as an objective marker of synovial membrane disease in RA.The thickness of synovium cannot predict the activity of RA.

关 键 词：关节炎 类风湿 超声检查 腕关节 滑膜 阻力指数 

分 类 号：R593.22[医药卫生—内科学] R445.1[医药卫生—临床医学]