超声时间与药材粒度对超声法提取槐花米中芦丁的影响  

Effect of time and particle size on yield of Rutin from Sophora japonica L. by ultrasonic-asisted extraction

作　　者：张宝璟[1] 张广元[2] 甄宇红[1] 于振龙[2] 黄珊珊[1] 马骁驰[1] 刁云鹏[1] 舒晓宏[1] 

机构地区：[1]大连医科大学药物化学教研室,辽宁大连116044 [2]大连医科大学药学院,2007级学生辽宁大连116044

出　　处：《大连医科大学学报》2010年第1期11-13,53,共4页Journal of Dalian Medical University

基　　金：辽宁省教委资助项目(No.2005L122);大连医科大学大学生科技创新项目

摘　　要：[目的]研究超声时间及药材粉碎粒度对超声法提取芦丁产率的影响,从而提高芦丁的提取效率。[方法]将不同粉碎粒度的槐花米粉末溶于碱液,超声提取不同时间后,检测不同时间点及不同粉碎粒度药材的芦丁产率,探索超声时间及粉碎粒度对芦丁提取产率的影响。[结果]粉碎至不同粒度的槐花米粉末,超声提取后所得芦丁产率在一定时间范围内均与超声时间正相关,而后呈平台趋势,在本实验条件下,采用3号筛的槐花米粉末超声5m in后即达到较高提取产率16.46%。[结论]药材粉碎粒度及超声时间对芦丁提取效率有着明显影响,超声辅助提取法较传统的碱提酸沉法具有流程短、效率高及成本低等优点。[ Objective ] To study the extraction time and the particle size of crude material which may have effects on the yield of rutin from Sophora japonica L. by ultrasonic -assisted extraction （UAE）. [ Methods ] The different particle sizes of S. japonica L. were extracted with alkali - water by UAE after pulverization, and the contents of rutin were detected at different times. [ Results ] The results showed that there was a positive correlation between the particle size of crude materials and the product yield of rutin within a certain time. After pulverized to the size of 3 sieves meshes and extracted for 5 minutes, the yield of rutin from Sophora japonica L. reached 16.4%. [ Conclusions] The time and the particle size have significantly effect on the yield of rutin from Sophora japonica L. by UAE. In comparison with the acid - base extraction, the UAE has advantage of short process, high - efficiency and low - cost.

关 键 词：芦丁 超声法 提取 

分 类 号：R284[医药卫生—中药学]