磁共振灌注成像诊断良恶性脑膜瘤  

MR perfusion weighted imaging in evaluation of benign and malignant meningiomas

作　　者：史瑞华[1] 翟仁友[1] 钱晓军[1] 鲁万红[1] 顾华[1] 

机构地区：[1]首都医科大学附属北京朝阳医院放射科,北京100020

出　　处：《中国医学影像技术》2010年第2期243-246,共4页Chinese Journal of Medical Imaging Technology

摘　　要：目的探讨脑膜瘤相对性脑血流容积(rCBV)与脑膜瘤良恶性间的关系。方法对36例经手术病理证实的脑膜瘤患者术前行常规MR及MR灌注成像(PWI)检查。PWI序列为GRE-EPI-T2*WI,原始灌注图像数据经工作站软件计算出脑血流容积(CBV)图,获取脑膜瘤最大rCBV值,分析良恶性脑膜瘤肿瘤实质区与周围水肿区间rCBV值的差异。结果良恶性脑膜瘤肿瘤实质区最大rCBV值分别为9.78±4.69、3.59±0.28(t=7.168,P<0.001);周围水肿区最大rCBV值分别为3.06±1.76、3.58±1.93(P>0.05)。结论MRPWI的rCBV值及CBV图是评价脑膜瘤良恶性的有价值的指标,对指导临床选择正确的治疗方案及评估预后具有重要意义。Objective To investigate the correlation between relative cerebral blood volume （rCBV） and tumor character of meningiomas. Methods Thirty-six （Grade Ⅰ： n = 30, Grade Ⅱ ＋Ⅲ： n = 6） patients with meningioma underwent conventional MR and perfusion weighted imaging （PWI） . The pulse sequence of PWI was single shot GRE-EPI-T2 WI. The CBV maps were calculated from the original data of perfusion images and the maximum rCBV of meningiomas was acquired from CBV maps through measurement on the region of interest （ROI） . The differences of rCBV in tumor and edema between benign and malignant tumors were analyzed. Results The mean rCBV in tumor of benign meningioma （9.78±4.69） was higher than that of malignant ones （3.59±0. 28） （t= 7. 168, P〈0. 001）. The mean rCBV in edema of benign and malignant meningiomas was 3.06± 1.76 and 3.58 ± 1.93, respectively （P〉0.05）. Conclusion CBV map and quantitative study of rCBV are feasible for differential diagnosis of meningiomas and have instructive function for clinical treatment and assessment of prognosis.

关 键 词：脑膜瘤 磁共振成像 灌注成像 相对性脑血流容积 

分 类 号：R445.2[医药卫生—影像医学与核医学] R739.41[医药卫生—诊断学]