局部内膜修整对体外受精-胚胎移植周期胚胎种植率的影响  

Local injury to the endometrium increases embryo implantation rates during in vitro fertilization-embryo transfer cycles

作　　者：李蓉[1] 杨伟洪[1] 王荣[1] 郝桂琴[1] 肖宇[1] 温烯[1] 

机构地区：[1]北京大学深圳医院生殖医学科,广东518036

出　　处：《生殖医学杂志》2010年第1期30-34,共5页Journal of Reproductive Medicine

摘　　要：目的探讨新鲜胚胎移植周期中子宫内膜修整对胚胎着床率、临床妊娠率和活产率的影响。方法回顾性分析宫腔镜术后体外受精-胚胎移植(IVF-ET)治疗患者,控制性超促排卵(controlled ovarian hyperstimulation,COH)过程中B超显示子宫内膜回声异常患者共417例,按其宫腔镜术后病理检查结果分为内膜正常组及内膜异常组。两组患者中各有一部分在COH过程中接受内膜修整(研究组),剩余为对照组。结果研究组胚胎着床率、临床妊娠率和活产率,均显著高于对照组。结论新鲜胚胎移植周期行子宫内膜修整可显著提高内膜回声异常患者的胚胎着床率、临床妊娠率和活产率。Objective： To explore the effects of local injury to the endometrium in in vitro fertilization （IVF） cycles on the rates of embryo implantation, clinical pregnancy and live birth. Methods： A tot retrospectively studie group） according to of 417 patients with abnormal ultrasonographic endometrial parameters were The patients were divided into two groups （normal and abnormal endometrium elr pa biopsy during the controlled thological results after hysteroscope. Parts of them underwent endometrial ovarian hyperstimulation （treatment group）, and those without biopsying served as control. Results： The rates of implantation, clinical pregnancy and live birth were significantly higher in the treatment groups than those in the controls. Conclusions： These results suggest that IVF treatment that is preceded by endometrial biopsy increase the rates of implantation, clinical pregnancy and live births in the patient with abnormal ultrasonographic endometrial parameters.

关 键 词：子宫内膜 胚胎着床 体外受精 局部损伤 胚胎移植 周期 试管婴儿 妊娠率 

分 类 号：S823.34[农业科学—畜牧学] Q492.6[农业科学—畜牧兽医]