肠易激综合征患者生命质量测定量表研制及评价  

Development and validation of quality of life instrument for patients with irritable bowel syndrome

作　　者：田建军[1] 周曾芬[2] 万崇华[3] 段丽萍[2] 李红缨[2] 李晓梅[3] 张晓磬[3] 

机构地区：[1]云南省昆明市延安医院消化内科,650051 [2]昆明医学院第一附属医院 [3]昆明医学院公共卫生学院

出　　处：《中国公共卫生》2010年第2期172-173,共2页Chinese Journal of Public Health

基　　金：国家自然科学基金(30360092)

摘　　要：目的研制与评价慢性病患者生命质量测定量表体系之肠易激综合征量表(QLICD-IBS)。方法采用程序化决策方式,结合中国人群背景,进行量表开发和研制;对99例肠易激综合征患者住院治疗前后的生命质量进行测评,评价量表效度、信度、反应度。结果肠易激综合征患者生命质量测定量表(QLICD-IBS)包括慢性病共性模块30个条目和肠易激综合征特异模块15个条目,量表各领域及维度的内部一致性信度(α)基本>0.6以上、重测信度(r)>0.9;各条目与所属维度及其领域的相关均大于与其他维度及领域的相关,相关系数(r)值大多>0.6;量表能够反映出患者治疗前后生命质量的变化。结论量表(QLICD-IBS)具有较好的信度、效度、反应度和临床可行性,可作为适合中国人群的生命质量测评工具。Objective To develop and validate the quality of life instrument for irritable bowel syndrome （ QLICD- IBS） patients. Methods The programmed decision-making method was used to develop a scale associated with domestic culture background. The psychometric properties of the instrument were evaluated by analyzing the data from 99 patients with irritable bowel syndrome. The statistic methods used in the research included Pearson correlation, factor analysis, cluster analysis and paired t student test. Results The QLICD-IBS was developed with 30 items of general module and 15 items of specific module. Most coefficients of internal consistency and test-retest reliability for facet and domain scores were above 0. 6 ; all of correlation coefficients between items and its facet and domain were higher than the item with other facets and domains; and most of the r values were above 0. 9. The scale had the ability to detect clinical change due to treatment. Conclusion The QLICD-IBS is valid,reliable,sensitive and reasonable for opearation in clinical settings and can be used to assess quality of life for patients with irritable bowel syndrome.

关 键 词：生命质量 肠易激综合征 克朗巴赫系数 

分 类 号：R574.4[医药卫生—消化系统]