大连沿海獐子岛地区高尿酸血症患病及影响因素分析  

Analysis on Prevalence and Influence Factors of Hyperuricemia Among Residents in Dalian Zhangzidao.

作　　者：侯桂梅[1] 罗兰[1] 程丽静[2] 高政南[1] 

机构地区：[1]辽宁省大连市中心医院,116033 [2]大连医科大学附属第二医院,116027

出　　处：《医学研究杂志》2010年第2期37-40,共4页Journal of Medical Research

基　　金：国家重点基础研究发展规划(973计划)项目(2006CB503901)

摘　　要：目的了解大连沿海獐子岛地区高尿酸血症患病情况及影响因素。方法采用整群与随机抽样相结合的方法抽取大连沿海獐子岛地区常住居民1021人,采用自制的问卷进行一般状况、生活方式及行为、家族史的调查,同时进行体格检查和相关生化指标的检测。应用SPSS13.0软件进行统计学分析。结果总患病率为9.50%,男性患病率为11.75%,显著高于女性(7.32%)。多因素非条件Logistic回归分析结果显示,性别、口味、高三酰甘油、中心型肥胖、低HDL血症等因素与高尿酸血症有关(P<0.05)。结论大连沿海獐子岛地区高尿酸血症患病率较高,且与多种因素有关。应采取综合干预措施进行防治,以降低患病率。Objective To assess the prevalence of hyperuricemia and its risk factors in Dalian Zhangzidao. Methods 1021 residents of Dalian Zhangzidao were randomly selected and examined. General conditions, life style, behaviors, and family histories were investigated. And physical examination and corresponding lab indexes were recorded. Data were analyzed by SPSS 13.0. Results The prevalence rate was 9.50% for all, with higher in men （ 11.75% ） than in women （7.32%） （X^2 = 5.83, P 〈 0.05 ）. The results of the Logistic regression showed that sex, taste, hypertriglyeeridemia, central obesity, hypohighdensitylipoproteinemia were the risk factors of hyperuricemia. Conclusion The prevalence rate of hyperurieemia in Dalian Zhangzidao was high. Health promotion on lifestyle change may help to incresse the public awareness and reduce the prevalence rate of hyperuricemia.

关 键 词：高尿酸血症 患病 危险因素 

分 类 号：R589.7[医药卫生—内分泌] R151.3[医药卫生—内科学]