肾脏皮质厚度、皮质容积大小与单肾功能相关性的64层SCT研究  

Relationship between Renal Cortex Thickness or Volume and Split Renal Function:Study with CT Measurement

作　　者：王云华[1] 刘瑞洪[2] 侯伟伟[1,3] 何建军[4] 支科[4] 

机构地区：[1]中南大学湘雅二医院放射科,长沙410011 [2]中南大学湘雅二医院肾内科,长沙410011 [3]湖南省肿瘤医院放诊科,410006 [4]中南大学湘雅二医院核医学科,长沙410011

出　　处：《临床放射学杂志》2010年第2期267-270,共4页Journal of Clinical Radiology

基　　金：2006年度湖南省科技计划项目资助(编号06SK3037)

摘　　要：目的研究肾脏皮质厚度、肾皮质容积大小与单肾功能的关系。资料与方法36例梗阻性肾积水患者,在对其行64层螺旋CT灌注扫描后行全肾CT增强扫描,并于2天内行单光子发射计算机体层成像(SPECT)肾动态显像检查。根据SPECT检测的肾小球滤过率(GFR)将72个肾脏分为正常组、肾功能轻度受损组、肾功能重度受损组,分别测量3组病例的肾脏皮质厚度、肾皮质容积大小均值;比较3组间64层SCT测量的肾脏皮质厚度、肾皮质容积大小的差异,分析肾脏皮质厚度、肾皮质容积大小与同侧肾GFR值的相关性,探讨64层SCT测量肾脏皮质厚度、肾皮质容积大小对单肾功能的评价价值。结果3组间肾脏皮质厚度分别为(0.51±0.1)cm、(0.37±0.12)cm、(0.23±0.80)cm,3组间肾脏皮质容积大小分别为(74.26±11.92)cm3、(55.28±15.19)cm3、(27.57±7.02)cm3。3组之间肾脏皮质厚度及容积大小差异均有统计学意义(F值分别为51.60,77.01,P值均<0.01)。肾脏皮质厚度、皮质容积大小与肾脏GFR均有良好的相关性(r=0.778与r=0.815,P值均<0.O1)。结论64层SCT增强扫描及相关后处理软件测量的肾脏皮质厚度与皮质容积大小能在一定程度上反映单肾功能,可以作为64层SCT评价单肾功能的有用参数。Objective To study the relationship between renal cortex thickness or volume and renal function,and to assess the value of CT as a criterion to grade renal function. Materials and Methods Enhanced CT were performed in 36 nephrohydrosis patients whose split renal glomerular filtration rate （GFR） were measured by SPECT renal dynamic imaging. The 72 kidneys were divided into normal renal function,mild and severe renal impairment groups according to renal function. Differences between the groups respect to the mean cortex thickness and volume were assesses by ANOVA.Using Pearson,scorrelation test,the corelation between the renal cortex thicknesses,volume and renal GFR were examined. Results The renal cortex thicknesses of normal renal function,mild and severe renal impairment groups were（0.51±0.1）、（0.37±0.12）、（0.23±0.80）cm respectively,and the renal cortex volume were（74.26±11.92）、（55.28±15.19）、（27.57±7.02）cm 3. There were significant differences of renal cortex thickness and volume between three groups （cortex thickness F=51.60,P〈0.01：cortex volume F=77.01,P〈0.01）,The thicknesses of renal cortex（ r=0.778,P〈0.01）,the volume of renal cortex （ r=0.815,P〈0.01） had positive linear corelation with renal function. Conclu-sion The thicknesses and volume of renal cortex measured by CT can reflect renal function. CT was a supplementary method to assess renal function.

关 键 词：肾皮质 肾皮质厚度 肾皮质容积 体层摄影术 X线计算机 梗阻性肾积水 肾小球滤过率 

分 类 号：R816.7[医药卫生—放射医学]