阵发性室上性心动过速急诊科不同治疗方法比较  

Compare the effects of different treatments on patients with paroxysmal supra-ventricular tachycardia in emergeny department

作　　者：张慧萍[1] 郭伟民[1] 魏晓霞[1] 阎新明[1] 卢彩兰[1] 

机构地区：[1]山西医科大学第二医院,山西太原030001

出　　处：《临床医药实践》2010年第1期23-25,共3页Proceeding of Clinical Medicine

基　　金：山西医科大学第二医院科技处技术新项目(项目编号:20090503)

摘　　要：目的:比较急诊科常用的4种治疗方法对阵发性室上性心动过速(PSVT)的疗效。方法:选择2007年8月—2009年3月急诊科诊断的236例PSVT患者,应用不同方法:迷走神经刺激法(对照组),去乙酰毛花苷,普罗帕酮和胺碘酮进行治疗,对比不同方法的有效转复率、转复时间及不良反应。结果:有效转复率,迷走神经刺激法为17.86%,去乙酰毛花苷为56.45%,普罗帕酮为74.14%,胺碘酮为93.33%。三组药物复律与迷走神经刺激法复律存在明显差异(P<0.05,P<0.01)。胺碘酮复律高于去乙酰毛花苷(P<0.01)和普罗帕酮(P<0.01)。转复时间:迷走神经刺激法最短,胺碘酮最长,二者比较差异有显著性(P<0.05),但胺碘酮与普罗帕酮复律时间无明显差异。不良反应发生率:迷走神经刺激法3.57%,去乙酰毛花苷17.74%,普罗帕酮10.34%,胺碘酮13.33%。与迷走神经刺激方法比较:去乙酰毛花苷差异有显著性(0.01<P<0.05),胺碘酮、普罗帕酮的不良反应差异无显著性。结论:复律,胺碘酮和普罗帕酮较高,去乙酰毛花苷次之,迷走神经刺激法最低。转复时间,迷走神经刺激法最短,胺碘酮最长。不良反应,短期应用普罗帕酮、胺碘酮的不良反应不明显,去乙酰毛花苷有明显的不良反应。Objective：To compare the effects of different treatment on patients with paroxysmal supraventricular tachycardia （PSVT）in emergency department. Methods：The data of 236 dmitted patients with PSVT who were treated with vagal veuro stimulation,cedilanid,propafenone and amiodarone from Aug. 2007 to Mar. 2009 were randomly col- lected. The effective cardioversion rates ,average cardioversion times and adverse reactions of treatment were analyzed retrospectively. Results： The effective eardioversion rates were： 17. 86%（vagal veuro stimulation）, 56. 45% （ cediland ）, 74. 14% （propafenone）, amiodarone （ 93.33 %）. Showing significant difference （P 〈 0.05, P〈 0.01 ）, amio darone was higher than eediland （P 〈 0.01 ）, propafenone （P〈0.01 ）. Cardioversion time ： vago neuro stimulation and amiodarone were significant difference （P 〈 0. 05, P 〈 0. 01 ）. Adverse reactions ： Comparing vago neuro stimulation, amiodarone and propafenone have no significant difference（P〉0. 5）while cedilanid have（0. 01〈P〈0. 05）. Conclu sions ：The effective cardioversion rates of propafenone and amiodarone were higher ,the next was cedilanid ,vago neuro stimulation was the lowest. Vago neuro stimulation was shortest,amiodarone requires longest time in cardoversion. Cedilanid have higher adverse reactions than amiodarone and propafenone.

关 键 词：阵发性室上性心动过速 迷走神经刺激法 去乙酰毛花苷 普罗帕酮 胺碘酮 

分 类 号：R541.71[医药卫生—心血管疾病]