糖皮质激素和长效β_2受体激动剂联合吸入治疗哮喘的疗效分析  

Effect of corticosteroid and long-acting β_2-agonist seretide on treating asthma

作　　者：童维佳[1] 

机构地区：[1]南京胸科医院药剂科,南京210029

出　　处：《实用药物与临床》2010年第1期67-69,共3页Practical Pharmacy and Clinical Remedies

摘　　要：目的分析糖皮质激素和长效β2受体激动剂联合吸入治疗哮喘的疗效。方法51例哮喘患者随机分为治疗组(糖皮质激素+长效β2受体激动剂组)和对照组(单用糖皮质激素组),分析治疗2周末、4周末的肺功能FEV1变化情况。结果治疗组治疗2周末、4周末肺功能FEV1的改变与对照组比较,差异有统计学意义(P<0.05)。结论联合吸入糖皮质激素+长效β2受体激动剂治疗哮喘较单用糖皮质激素有效。Objective To observe the effect of corticosteroid and long-acting β2-agonist on treating patients with moderate asthma who were uncontrolled on existing corticosteroid therapy. Methods 51 patients Were randomly divided into two groups, treatment group was treated with symbicort and the control group was treated with pulmicort （budesonide）. The clinical effect index and forced expiratory volume in one second（ FEVl ）were analyzed after two and four weeks. Results Compared with control groups,there was significant difference of the patients＇ FEV1 after two and four weeks therapy（ P 〈 0. 05）. Conclusion Corticosteroid combined with long-acting β2-agonist seretide is effective for asthma.

关 键 词：糖皮质激素 长效Β2受体激动剂 哮喘 

分 类 号：R562.25[医药卫生—呼吸系统]