PET／CT联合HRCT对肺孤立结节的鉴别诊断价值  

The value of differential diagnosis in solitary pulmonary nodule with PET/CT combining HRCT

作　　者：陆佩欧[1] 于丽娟[1] 孙亚娟[1] 梁秀艳[1] 刘蕊[1] 贾承晔[1] 

机构地区：[1]哈尔滨医科大学附属肿瘤医院PET/CT中心,哈尔滨150081

出　　处：《实用肿瘤学杂志》2010年第1期15-19,共5页Practical Oncology Journal

基　　金：基金项目：黑龙江省教育厅科学技术研究面上项目（11521175）

摘　　要：目的评价PET／CT联合HRCT对肺孤立结节（SPN）的鉴别诊断价值。方法60例SPN经常规PET-CT扫描加肺结节局部薄层高分辨CT扫描（以下简称为HRCT），所有结节均经病理证实。PET／CT根据结节PET的代谢特点和同时平静呼吸低剂量CT的形态学特点综合判定；PET／CT联合HRCT则在PET／CT诊断的基础上综合HRCT的CT征象判定。结果PET／CT和PET／CT联合HRCT诊断SPN的敏感性、特异性、准确性分别为89．5％、77．3％、85．0％和97．4％、81．8％和91．7％。结论PET／CT联合HRCT可以提高PET／CT诊断孤立肺结节的敏感性、特异性和准确性。Objective To evaluate the value of differential diagnosis in solitary, pulmonary nodule （SPN） with HRCT and 18F - FDG PET/CT. Methods 60 solitary pulmonary nodules were examined with 18F - FDG PET/CT and local thin -slice high resolution CT（ LTHRCT, for short HRCT） , all of which were proven pathologically. The diagnosis of PET/CT relied on the metabolism feature of PET and the morphology feature in low - dose CT during quiet respiration. The diagnosis of PET/CT combining HRCT considered the morphology feature of HRCT on the basis of PET/CT. Results The sensitivity,specificity,accuracy of PET/CT were 89.5% ,77.3% and 85.0% respectively, accordingly, the sensitivity, specificity, accuracy of PET/CT combining HRCT were 97.4% , 81.8% and 91.7% respectively. Conclusions PET/CT combining HRCT can raise the sensitivity, specificity and accuracy of PET/CT in the diagnosis of SPN.

关 键 词：肺孤立结节 体层摄影术 发射单光子计算机断层扫描仪 X-线计算机 扫描仪 

分 类 号：R445.6[医药卫生—影像医学与核医学]