正交实验法优选复方三七胶囊的提取工艺  

Orthogonal design for optimizing extraction process of Compound Sanqi Capsule

作　　者：吉江华[1] 胡芳[2] 程建明[2] 

机构地区：[1]淮安市楚州医院,江苏淮安223200 [2]南京中医药大学,江苏南京210029

出　　处：《现代医药卫生》2010年第6期835-836,共2页Journal of Modern Medicine & Health

摘　　要：目的:优选复方三七胶囊的提取工艺。方法:采用L9(34)正交试验,以人参皂苷Rg1转移率和出固率为指标,考察提取用醇浓度、加醇量、提取时间对提取效果的影响。结果:最佳工艺为药材加70%乙醇,提取两次,第一次用8倍量,第二次用7倍量,每次提取1小时。结论:本法为复方三七胶囊醇提工艺的确定提供实验依据。Objective：To optimize the extraction process Compound Sanqi Capsule.Methods：Using the orthogonal method,the main factors affecting the ethanol-extraction process,such as the content of ethanol,the quantity of ethanol and the time for decoction, were investigated with ginsenoside Rgl transfer rate and yield rate as the indexes.Results：The optimum condition of ethanol -extraction was extracting with 8 times amount of ethanol for first time and with 7 times amount for second time, 1 h each time.Conclution：The experimental results provide the basis for the ethanol extraction process Compound Sanqi Capsule.

关 键 词：复方三七胶囊 人参皂苷RG1 正交试验 

分 类 号：R28[医药卫生—中药学]