中药产复康对大鼠离体子宫平滑肌收缩功能的影响  

Effects of Chinese herbal medicine Chanfukang on in vitro uterine smooth muscle contraction in rats

作　　者：严作廷[1] 王东升[1] 杨国林[1] 谢家声[1] 李世宏[1] 梁纪兰[1] 余四九[2] 李倬[3] 周晓兰[3] 

机构地区：[1]中国农业科学院兰州畜牧与兽药研究所,甘肃兰州730050 [2]甘肃农业大学动物医学院 [3]西北民族大学生命科技学院

出　　处：《中兽医医药杂志》2010年第1期10-13,共4页Journal of Traditional Chinese Veterinary Medicine

基　　金：国家科技攻关项目奶业专项"奶牛主要疫病防治关键技术研究与产业化开发"子课题"预防奶牛子宫内膜炎中药或中西结合药剂的研制"(项目编号:2002BA518A04)资助

摘　　要：为了观察中药制剂产复康对离体子宫平滑肌的收缩功能,测定了产复康对大鼠离体子宫平滑肌收缩功能和催产素引起的大鼠离体子宫平滑肌收缩功能的影响。结果发现低剂量产复康可以促进大鼠离体子宫平滑肌的收缩功能,提高子宫的活动性,高剂量则对子宫呈抑制作用;产复康对催产素引起的大鼠离体子宫平滑肌收缩功能具有抑制作用,且呈剂量-效应关系。产复康对大鼠离体子宫具有双向调节作用。The effects of Chinese herbal medicine Chanfukang on uterine smooth muscle contraction and uterine smooth muscle contraction function induced by oxytocin were observed in rats. The result showed that the low dose of Chanfukang could promote uterine smooth muscle contraction function and the reactiveness of uterine in vitro,while the high dose could inhibit uterine smooth muscle contraction function in rats. Chanfukang could inhibit the uterine smooth muscle contraction function induced by oxytocin and showed a relation of dose-effect. The results indicated Chinese herbal medicine Chanfukang have two-side regulation effect on in vitro uterine smooth muscle in rats.

关 键 词：大鼠 离体子宫 产复康 

分 类 号：S853.74[农业科学—临床兽医学]